AbstractStudies with transgenic mice are beginning to define the minimal requirements for the somatic hypermutation of immunoglobulin genes that is critical in the production of high-affinity antibodies
Evidence for somatic hypermutation of immunoglobulin genes has been observed in all of the species i...
Allelic exclusion of IgH chain expression is stringently established before or during early B cell m...
AbstractThe frequency of somatic hypermutations of an Ig κ transgene with an artificial test insert,...
AbstractStudies with transgenic mice are beginning to define the minimal requirements for the somati...
AbstractSomatic hypermutation is critical for the generation of high-affinity antibodies and effecti...
AbstractSomatic hypermutation contributes to the generation of antibody diversity and is strongly as...
AbstractTo identify DNA sequences that target the somatic hypermutation process, the immunoglobulin ...
AbstractHow rearranged immunoglobulin (Ig) genes are further diversified by somatic hypermutation is...
Somatic hypermutation of immunoglobulin genes is an important contributor to antibody diversity. Lac...
AbstractRecent studies have investigated whether particular DNA repair pathways are involved in the ...
While somatic antibody mutants are rare in the preimmune repertoire and in primary immune responses,...
Somatic hypermutation of immunoglobulin genes is a tightly controlled, site directed process. The nu...
AbstractSomatic hypermutation (SHM) requires selective targeting of the mutational machinery to the ...
AbstractThree mutant immunoglobulin heavy chain (IgH) insertion mice were generated in which a targe...
AbstractAs the rate of Ig gene hypermutation approximates the level of nucleotide discrimination of ...
Evidence for somatic hypermutation of immunoglobulin genes has been observed in all of the species i...
Allelic exclusion of IgH chain expression is stringently established before or during early B cell m...
AbstractThe frequency of somatic hypermutations of an Ig κ transgene with an artificial test insert,...
AbstractStudies with transgenic mice are beginning to define the minimal requirements for the somati...
AbstractSomatic hypermutation is critical for the generation of high-affinity antibodies and effecti...
AbstractSomatic hypermutation contributes to the generation of antibody diversity and is strongly as...
AbstractTo identify DNA sequences that target the somatic hypermutation process, the immunoglobulin ...
AbstractHow rearranged immunoglobulin (Ig) genes are further diversified by somatic hypermutation is...
Somatic hypermutation of immunoglobulin genes is an important contributor to antibody diversity. Lac...
AbstractRecent studies have investigated whether particular DNA repair pathways are involved in the ...
While somatic antibody mutants are rare in the preimmune repertoire and in primary immune responses,...
Somatic hypermutation of immunoglobulin genes is a tightly controlled, site directed process. The nu...
AbstractSomatic hypermutation (SHM) requires selective targeting of the mutational machinery to the ...
AbstractThree mutant immunoglobulin heavy chain (IgH) insertion mice were generated in which a targe...
AbstractAs the rate of Ig gene hypermutation approximates the level of nucleotide discrimination of ...
Evidence for somatic hypermutation of immunoglobulin genes has been observed in all of the species i...
Allelic exclusion of IgH chain expression is stringently established before or during early B cell m...
AbstractThe frequency of somatic hypermutations of an Ig κ transgene with an artificial test insert,...