SummaryROP/RAC GTPases are master regulators of cell polarity in plants, implicated in the regulation of diverse signaling cascades including cytoskeleton organization, vesicle trafficking, and Ca2+ gradients [1–8]. The involvement of ROPs in differentiation processes is yet unknown. Here we show the identification of a novel ROP/RAC effector, designated interactor of constitutive active ROPs 1 (ICR1), that interacts with GTP-bound ROPs. ICR1 knockdown or silencing leads to cell deformation and loss of root stem-cell population. Ectopic expression of ICR1 phenocopies activated ROPs, inducing cell deformation of leaf-epidermis-pavement and root-hair cells [3, 5, 6, 9]. ICR1 is comprised of coiled-coil domains and forms complexes with itself ...
SummaryCoordinating growth and communication between adjacent cells is a critical yet poorly underst...
Spatially restricted signaling by Rho GTPases is essential for the polarization of eukaryotic cells,...
RHO guanosine triphosphatases are important eukaryotic regulators of cell differentiation and behavi...
SummaryROP/RAC GTPases are master regulators of cell polarity in plants, implicated in the regulatio...
Development in multicellular organisms depends on the ability of individual cells to coordinate thei...
Development in multicellular organisms depends on the ability of individual cells to coordinate thei...
Root hairs (RHs) grow in a polar manner as cylindrical protrusions from the root epidermis. They sig...
Cell polarity is a prerequisite for the formation of distinct cell shapes, which allow different cel...
Small GTP-binding proteins are molecular switches that serve as important regulators of numerous cel...
Cell polarization via asymmetrical distribution of structures or molecules is essential for diverse ...
Plant RHO GTPases (RAC/ROPs) mediate multiple extracellular signals ranging from hormone to stress a...
AbstractPlants lack the Rho and Rac/Cdc42 GTPases that are so important in diverse signal transducti...
ROP (Rho-like GTPases from plants) GTPases are polarly localized key regulators of polar growth in p...
SummaryCortical microtubules (MTs) participate in the spatial control of cell expansion and division...
KEY MESSAGE: Several amino acid motifs required for Rop-dependent activity were found to form a comm...
SummaryCoordinating growth and communication between adjacent cells is a critical yet poorly underst...
Spatially restricted signaling by Rho GTPases is essential for the polarization of eukaryotic cells,...
RHO guanosine triphosphatases are important eukaryotic regulators of cell differentiation and behavi...
SummaryROP/RAC GTPases are master regulators of cell polarity in plants, implicated in the regulatio...
Development in multicellular organisms depends on the ability of individual cells to coordinate thei...
Development in multicellular organisms depends on the ability of individual cells to coordinate thei...
Root hairs (RHs) grow in a polar manner as cylindrical protrusions from the root epidermis. They sig...
Cell polarity is a prerequisite for the formation of distinct cell shapes, which allow different cel...
Small GTP-binding proteins are molecular switches that serve as important regulators of numerous cel...
Cell polarization via asymmetrical distribution of structures or molecules is essential for diverse ...
Plant RHO GTPases (RAC/ROPs) mediate multiple extracellular signals ranging from hormone to stress a...
AbstractPlants lack the Rho and Rac/Cdc42 GTPases that are so important in diverse signal transducti...
ROP (Rho-like GTPases from plants) GTPases are polarly localized key regulators of polar growth in p...
SummaryCortical microtubules (MTs) participate in the spatial control of cell expansion and division...
KEY MESSAGE: Several amino acid motifs required for Rop-dependent activity were found to form a comm...
SummaryCoordinating growth and communication between adjacent cells is a critical yet poorly underst...
Spatially restricted signaling by Rho GTPases is essential for the polarization of eukaryotic cells,...
RHO guanosine triphosphatases are important eukaryotic regulators of cell differentiation and behavi...