Isoniazid metabolism and hepatotoxicity
- Wang, Pengcheng
- Pradhan, Komal
- Zhong, Xiao-bo
- Ma, Xiaochao
Publication date
September 2016
DOI Publisher
Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V. ISSN
2211-3835 Citation count (estimate)
17Abstract
AbstractIsoniazid (INH) is highly effective for the management of tuberculosis. However, it can cause liver injury and even liver failure. INH metabolism has been thought to be associated with INH-induced liver injury. This review summarized the metabolic pathways of INH and discussed their associations with INH-induced liver injury
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