Human induced pluripotent stem cells represent a promising tool for investigating the underlying causes of disease; however, this potential currently remains unfulfilled. In this issue of Cell Stem Cell, Yoon et al. (2014) used iPSCs derived from patients harboring common genetic risk variants as the starting point to discover novel insights into disease pathology
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disea...
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disea...
The discovery of induced pluripotent stem (iPS) cells has broadened the promises of regenerative med...
SummaryGenome editing has attracted wide interest for the generation of cellular models of disease u...
Genome editing has attracted wide interest for the generation of cellular models of disease using hu...
It is extremely rare for a single experiment to be so impactful and timely that it shapes and foreca...
SummaryThe utility of genome editing technologies for disease modeling and developing cellular thera...
Human induced pluripotent stem cells represent a promising tool for investigating the underlying cau...
Defined transcription factors can induce epigenetic reprogramming of adult mammalian cells into indu...
Two recent studies report the generation of induced pluripotent stem cells from patients presenting ...
Mechanistic insights into human disease may enable the development of treatments that are effective ...
The possibility to generate patient-specific induced pluripotent stem cells (iPSCs) offers an unprec...
<div><p>The accuracy of replicating the genetic code is fundamental. DNA repair mechanisms protect t...
Two recent reports describe promising, highly efficient methods to modify genes in pluripotent stem ...
Human pluripotent stem cells (PSCs) are subject to the appearance of recurrent genetic variants on p...
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disea...
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disea...
The discovery of induced pluripotent stem (iPS) cells has broadened the promises of regenerative med...
SummaryGenome editing has attracted wide interest for the generation of cellular models of disease u...
Genome editing has attracted wide interest for the generation of cellular models of disease using hu...
It is extremely rare for a single experiment to be so impactful and timely that it shapes and foreca...
SummaryThe utility of genome editing technologies for disease modeling and developing cellular thera...
Human induced pluripotent stem cells represent a promising tool for investigating the underlying cau...
Defined transcription factors can induce epigenetic reprogramming of adult mammalian cells into indu...
Two recent studies report the generation of induced pluripotent stem cells from patients presenting ...
Mechanistic insights into human disease may enable the development of treatments that are effective ...
The possibility to generate patient-specific induced pluripotent stem cells (iPSCs) offers an unprec...
<div><p>The accuracy of replicating the genetic code is fundamental. DNA repair mechanisms protect t...
Two recent reports describe promising, highly efficient methods to modify genes in pluripotent stem ...
Human pluripotent stem cells (PSCs) are subject to the appearance of recurrent genetic variants on p...
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disea...
Genetic integrity of induced pluripotent stem cells (iPSCs) is essential for their validity as disea...
The discovery of induced pluripotent stem (iPS) cells has broadened the promises of regenerative med...