212: Death and cardiovascular events in patients with acute coronary syndrome and abdominal aortic aneurysm

BackgroundAbdominal aortic aneurysm (AAA) is associated with peripheral and coronary artery disease (CAD), however little is known about the prognosis of patients who experienced an acute coronary syndrome (ACS) and have an AAA. The aim of this study was to assess the prevalence of AAA in patients hospitalized for ACS and to evaluate it was associated with an increased cardio-vascular (CV) risk during follow up.MethodsBetween February 1, 2008 and March 30, 2009, patients admitted for ACS with significant (≥50% stenosis) coronary lesions underwent echography to check for presence of AAA. The AAA was defined as dilation of infrarenal aorta with maximum antero-posterior diameter ≥30mm. During a 2 years follow-up we recorded all causes death, CV death and non-fatals CV events. The combination of CV death and CV non-fatals events was defined as the primary endpoint.ResultsAmong 306 patients, 20 AAAs (6,6%) were diagnosed, of average (±sd) diameter 33±3.7mm, with a maximum diameter of 45mm, non requiring surgery. Follow-up at 2 years was available for 292 patients (95,7%). During follow-up, 77 patients (25,5%) experienced an event (all causes death or non-fatals CV event) : 23 deaths (7,6%), of wich 16 were from CV cause, and 55 non-fatals CV event (18,2%). No event was due to AAA. In univariate analysis age, abdominal aortic diameter, diabetes mellitus, previously known CAD and AAA were significantly associated with fatal and non-fatal CV event (p