Diagnostic Accuracy of Coronary In-Stent Restenosis Using 64-Slice Computed Tomography Comparison With Invasive Coronary Angiography

ObjectivesThis study sought to evaluate the diagnostic accuracy of coronary binary in-stent restenosis (ISR) with angiography using 64-slice multislice computed tomography coronary angiography (CTCA) compared with invasive coronary angiography (ICA).BackgroundA noninvasive detection of ISR would result in an easier and safer way to conduct patient follow-up.MethodsWe performed CTCA in 81 patients after stent implantation, and 125 stented lesions were scanned. Two sets of images were reconstructed with different types of convolution kernels. On CTCA, neointimal proliferation was visually evaluated according to luminal contrast attenuation inside the stent. Lesions were graded as follows: grade 1, none or slight neointimal proliferation; grade 2, neointimal proliferation with no significant stenosis (