In a quantitative study we have compared the serum levels, the time course and the photosensitizing capacity of a conventional crystalline 8-methoxypsoralen brand and an investigational liquid formula. Evidence is presented showing that the liquid preparation is superior to the crystalline form: it peaks earlier after ingestion, it produces higher and more reproducible serum concentrations and thus a more constant degree of photosensitization, it is eliminated more rapidly from the blood, and it requires a lower UV-A dose for eliciting photosensitivity reactions aiming at a reduction of the total cumulative UV-A dose required for clearing psoriasis
E' stato effettuato uno studio comparativo dei profili plasmatici di 8-metossipsoralene (8-MOP) somm...
Two medically useful photosensitizing furocoumarins, 8-methoxypsoralen (8-MOP) and 4,5′8-trimethylps...
During the last decade psoralens have become increasingly popular in treating psoriasis. The well-kn...
In a quantitative study we have compared the serum levels, the time course and the photosensitizing ...
Serum levels and skin photosensitivity following different oral doses of 8-methoxypsoralen (8-MOP) w...
Photoactive 8-methoxypsoralen (8-MOP) levels in human and animal sera were determined by bioassay wi...
A new encapsulated liquid preparation of methoxsalen (8-MOP) and a commonly used crystalline prepara...
We have simultaneously measured plasma levels of 8-methoxypsoralen (8-MOP) and photosensitivity to l...
There is considerable interindividual variation in bioavailability of Methoxsalen (8-methoxypsoralen...
There is considerable interindividual variation in bioavailability of Methoxsalen (8-methoxypsoralen...
Background We recently investigated the characteristics of psoralen plus ultraviolet (UV) A erythema...
In six healthy volunteers the 8-methoxypsoralen (8-MOP) plasma levels have been determined by high r...
We have adapted a rapid and sensitive high-pressure liquid chromatographic technique (HPLC) to measu...
A method is described to determine the 8-methoxy-psoralen (8-MOP) concentration in vivo in the skin ...
The molecular basis for the clinically observed differences in the skin photosensitizing activity an...
E' stato effettuato uno studio comparativo dei profili plasmatici di 8-metossipsoralene (8-MOP) somm...
Two medically useful photosensitizing furocoumarins, 8-methoxypsoralen (8-MOP) and 4,5′8-trimethylps...
During the last decade psoralens have become increasingly popular in treating psoriasis. The well-kn...
In a quantitative study we have compared the serum levels, the time course and the photosensitizing ...
Serum levels and skin photosensitivity following different oral doses of 8-methoxypsoralen (8-MOP) w...
Photoactive 8-methoxypsoralen (8-MOP) levels in human and animal sera were determined by bioassay wi...
A new encapsulated liquid preparation of methoxsalen (8-MOP) and a commonly used crystalline prepara...
We have simultaneously measured plasma levels of 8-methoxypsoralen (8-MOP) and photosensitivity to l...
There is considerable interindividual variation in bioavailability of Methoxsalen (8-methoxypsoralen...
There is considerable interindividual variation in bioavailability of Methoxsalen (8-methoxypsoralen...
Background We recently investigated the characteristics of psoralen plus ultraviolet (UV) A erythema...
In six healthy volunteers the 8-methoxypsoralen (8-MOP) plasma levels have been determined by high r...
We have adapted a rapid and sensitive high-pressure liquid chromatographic technique (HPLC) to measu...
A method is described to determine the 8-methoxy-psoralen (8-MOP) concentration in vivo in the skin ...
The molecular basis for the clinically observed differences in the skin photosensitizing activity an...
E' stato effettuato uno studio comparativo dei profili plasmatici di 8-metossipsoralene (8-MOP) somm...
Two medically useful photosensitizing furocoumarins, 8-methoxypsoralen (8-MOP) and 4,5′8-trimethylps...
During the last decade psoralens have become increasingly popular in treating psoriasis. The well-kn...