Solvent free synthesis of 3,4-dihydropyrimidine-2-(1H)-ones/thiones catalyzed by N,O-bis(trimethylsilyl)acetamide and dicyclohexyl carbodimide
- Murthy, Y.L.N.
- Rajack, Abdul
- Yuvaraj, Kanithi
Publication date
November 2016
DOI Publisher
Production and hosting by Elsevier B.V. on behalf of King Saud University. ISSN
1878-5352 Citation count (estimate)
2Abstract
AbstractWe report herein, the usage of N,O-bis(trimethylsilyl)acetamide (BSA) and dicyclohexyl carbodimide (DCC) as two new catalysts for three component condensation of an aldehyde, ethyl acetoacetate and urea/thiourea under solvent free conditions at 100°C to afford the corresponding 3,4-dihydropyrimidine-2-(1H)-ones/thiones (DHPMs) in good to excellent yields. A comparative study of these two catalysts was made and presented
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