AbstractGalactosylceramide (GalCer), a glycosphingolipid, is believed to exist in the extracellular leaflet of cell membranes in nanometer-sized domains or rafts. The local clustering of GalCer within rafts is thought to facilitate the initial adhesion of certain viruses, including HIV-1, and bacteria to cells through multivalent interactions between receptor proteins (gp120 for HIV-1) and GalCer. Here we use atomic force microscopy (AFM) to study the effects of cholesterol on solid-phase GalCer domain microstructure and miscibility with a fluid lipid 1,2-dilauroyl-sn-glycero-3-phosphocholine (DLPC) in supported lipid bilayers. Using “slow-cooled vesicle fusion” to prepare the supported lipid bilayers, we were able to overcome the nonequili...
AbstractSeveral studies suggest that the plasma membrane is composed of micro-domains of saturated l...
AbstractWe have compared the domain forming properties of three neutral acyl chain defined glycosphi...
AbstractThe glycosphingolipid globotriaosyl ceramide, (Galα1-4Galß1-4 glucosyl ceramide-Gb3) also kn...
Galactosylceramide (GalCer), a glycosphingolipid, is believed to exist in the extracellular leaflet ...
AbstractGalactosylceramide (GalCer), a glycosphingolipid, is believed to exist in the extracellular ...
AbstractDomains within the plane of the plasma membrane, referred to as membrane rafts, have been a ...
AbstractWe report the microstructure and phase behavior of three ternary mixtures each containing a ...
AbstractCholesterol plays a crucial role in cell membranes, and has been implicated in the assembly ...
AbstractIntrinsic heterogeneities, represented as domain formations in biological membranes, are imp...
AbstractAtomic force microscopy has been used to study the distribution of ganglioside GM1 in model ...
ABSTRACT Cholesterol plays a crucial role in cell membranes, and has been implicated in the assembly...
Even in small amounts, glycolipids are an integral part of lipid rafts and their cellular functions....
Galactosylceramides (GalCer) are glycosphingolipids bound to a monosaccharide group, responsible for...
AbstractThe distribution of low concentrations of ganglioside GM1 in l-α-dipalmitoylphosphatidylchol...
AbstractCholesterol is believed to be an important component in compositionally distinct lipid domai...
AbstractSeveral studies suggest that the plasma membrane is composed of micro-domains of saturated l...
AbstractWe have compared the domain forming properties of three neutral acyl chain defined glycosphi...
AbstractThe glycosphingolipid globotriaosyl ceramide, (Galα1-4Galß1-4 glucosyl ceramide-Gb3) also kn...
Galactosylceramide (GalCer), a glycosphingolipid, is believed to exist in the extracellular leaflet ...
AbstractGalactosylceramide (GalCer), a glycosphingolipid, is believed to exist in the extracellular ...
AbstractDomains within the plane of the plasma membrane, referred to as membrane rafts, have been a ...
AbstractWe report the microstructure and phase behavior of three ternary mixtures each containing a ...
AbstractCholesterol plays a crucial role in cell membranes, and has been implicated in the assembly ...
AbstractIntrinsic heterogeneities, represented as domain formations in biological membranes, are imp...
AbstractAtomic force microscopy has been used to study the distribution of ganglioside GM1 in model ...
ABSTRACT Cholesterol plays a crucial role in cell membranes, and has been implicated in the assembly...
Even in small amounts, glycolipids are an integral part of lipid rafts and their cellular functions....
Galactosylceramides (GalCer) are glycosphingolipids bound to a monosaccharide group, responsible for...
AbstractThe distribution of low concentrations of ganglioside GM1 in l-α-dipalmitoylphosphatidylchol...
AbstractCholesterol is believed to be an important component in compositionally distinct lipid domai...
AbstractSeveral studies suggest that the plasma membrane is composed of micro-domains of saturated l...
AbstractWe have compared the domain forming properties of three neutral acyl chain defined glycosphi...
AbstractThe glycosphingolipid globotriaosyl ceramide, (Galα1-4Galß1-4 glucosyl ceramide-Gb3) also kn...