AbstractAn optimization principle is proposed for the regulation of vascular morphology. This principle, which extends Murray's law, is based on the hypothesis that blood vessel diameter is controlled by a mechanism that minimizes the total energy required to drive the blood flow, to maintain the blood supply, and to support smooth muscle tone. A theoretical analysis reveals that the proposed principle predicts that the optimum shear stress on the vessel wall due to blood flow increases with blood pressure. This result agrees qualitatively with published findings that the fluid shear stress in veins is significantly smaller than it is in arteries
<div><p>Organ perfusion is regulated by vasoactivity and structural adaptation of small arteries and...
We propose a design principle that extends Murray's original optimization principle for vascular arc...
Organ perfusion is regulated by vasoactivity and structural adaptation of small arteries and arterio...
AbstractAn optimization principle is proposed for the regulation of vascular morphology. This princi...
We propose a design principle that extends Murray's original optimization principle for vascular arc...
Background Murray's Law states that, when a parent blood vessel branches into daughter vessels, the ...
SUMMARY- The principle of minimum work (PMW) is a parametric optimization model for the growth and a...
SYNOPSIS. Hematocrit is likely to be optimized because of its influences on oxygen transport. Howeve...
Understanding of vascular organization is a long-standing problem in quantitative biology and biophy...
Abstract. We build an evolutionary scenario that explains the selection of core physiological quanti...
© The Author(s) 2014. This article is published with open access at Springerlink.com Abstract A goal...
radii in muscular blood vessels. Am. J. PhysioZ. 271 (Heart Circ. PhysioZ. 40): H2669-H2676,1996.-A ...
We propose a design principle that extends Murray's original optimization principle for vascular arc...
Diameters of microvessels undergo continuous structural adaptation in response to hemodynamic and me...
In normal tissues, blood supply is closely matched to tissue demand for wide ranges of oxygen demand...
<div><p>Organ perfusion is regulated by vasoactivity and structural adaptation of small arteries and...
We propose a design principle that extends Murray's original optimization principle for vascular arc...
Organ perfusion is regulated by vasoactivity and structural adaptation of small arteries and arterio...
AbstractAn optimization principle is proposed for the regulation of vascular morphology. This princi...
We propose a design principle that extends Murray's original optimization principle for vascular arc...
Background Murray's Law states that, when a parent blood vessel branches into daughter vessels, the ...
SUMMARY- The principle of minimum work (PMW) is a parametric optimization model for the growth and a...
SYNOPSIS. Hematocrit is likely to be optimized because of its influences on oxygen transport. Howeve...
Understanding of vascular organization is a long-standing problem in quantitative biology and biophy...
Abstract. We build an evolutionary scenario that explains the selection of core physiological quanti...
© The Author(s) 2014. This article is published with open access at Springerlink.com Abstract A goal...
radii in muscular blood vessels. Am. J. PhysioZ. 271 (Heart Circ. PhysioZ. 40): H2669-H2676,1996.-A ...
We propose a design principle that extends Murray's original optimization principle for vascular arc...
Diameters of microvessels undergo continuous structural adaptation in response to hemodynamic and me...
In normal tissues, blood supply is closely matched to tissue demand for wide ranges of oxygen demand...
<div><p>Organ perfusion is regulated by vasoactivity and structural adaptation of small arteries and...
We propose a design principle that extends Murray's original optimization principle for vascular arc...
Organ perfusion is regulated by vasoactivity and structural adaptation of small arteries and arterio...