The management of cyclosporine A (CsA)-induced nephrotoxicity remains one of the main challenges in kidney transplantation. The animal study by Park et al. proposes that paricalcitol, a vitamin D analog with renoprotective actions reported in other conditions, attenuates CsA-induced kidney injury via the suppression of inflammatory, fibrotic, and apoptotic factors. Before paricalcitol can be considered a feasible new therapeutic option for post-transplantation nephropathy, these interesting data require further studies assessing other mechanisms of CsA-induced nephrotoxicity
IntroductionCyclosporine-induced Nephrotoxicity (CIN) is a major adverse event but its pathophysiolo...
In six of twelve orthotopic liver recipients nephrotoxicity was noted after 13-22 days of treatment ...
Side-effect minimization strategies to avoid serious side-effects of cyclosporine A (CsA), such as n...
The management of cyclosporine A (CsA)-induced nephrotoxicity remains one of the main challenges in ...
Despite its benefits, the clinical use of cyclosporine A (CsA) is limited by its nephrotoxic propert...
BACKGROUND: Nephrotoxicity of calcineurin inhibitors (CNIs) is partially responsible for the develop...
The discovery and use of cyclosporine since its inception into clinical use in the late 1970s has pl...
BACKGROUND: Chronic allograft nephropathy (CAN) represents the most common cause of late graft loss...
The outcome of solid organ transplantation has improved significantly in the past few decades with t...
Sirolimus, a macrocylic lactone, blocks T-cell activation by a mechanism of action distinct from cal...
Long-term survival of kidney transplants (renal allografts) has changed little during the past decad...
Nature and mediators of renal lesions in kidney transplant patients given cyclosporine for more than...
AbstractThe outcome of solid organ transplantation has improved significantly in the past few decade...
Cyclosporine elimination in a regimen including sirolimus has been shown to be a safe and effective ...
High coronary artery calcification score (CACS) assessed by computed tomography is related to mortal...
IntroductionCyclosporine-induced Nephrotoxicity (CIN) is a major adverse event but its pathophysiolo...
In six of twelve orthotopic liver recipients nephrotoxicity was noted after 13-22 days of treatment ...
Side-effect minimization strategies to avoid serious side-effects of cyclosporine A (CsA), such as n...
The management of cyclosporine A (CsA)-induced nephrotoxicity remains one of the main challenges in ...
Despite its benefits, the clinical use of cyclosporine A (CsA) is limited by its nephrotoxic propert...
BACKGROUND: Nephrotoxicity of calcineurin inhibitors (CNIs) is partially responsible for the develop...
The discovery and use of cyclosporine since its inception into clinical use in the late 1970s has pl...
BACKGROUND: Chronic allograft nephropathy (CAN) represents the most common cause of late graft loss...
The outcome of solid organ transplantation has improved significantly in the past few decades with t...
Sirolimus, a macrocylic lactone, blocks T-cell activation by a mechanism of action distinct from cal...
Long-term survival of kidney transplants (renal allografts) has changed little during the past decad...
Nature and mediators of renal lesions in kidney transplant patients given cyclosporine for more than...
AbstractThe outcome of solid organ transplantation has improved significantly in the past few decade...
Cyclosporine elimination in a regimen including sirolimus has been shown to be a safe and effective ...
High coronary artery calcification score (CACS) assessed by computed tomography is related to mortal...
IntroductionCyclosporine-induced Nephrotoxicity (CIN) is a major adverse event but its pathophysiolo...
In six of twelve orthotopic liver recipients nephrotoxicity was noted after 13-22 days of treatment ...
Side-effect minimization strategies to avoid serious side-effects of cyclosporine A (CsA), such as n...