AbstractThe lung is an organ with a large inner surface that is continuously in contact with the environment. Infection of this organ is prevented by several mechanisms. A recently described defence system is collectin-mediated innate immunity of the lung. Collectins are multimeric proteins characterized by carbohydrate recognition domains bound to collagen stalks. Surfactant protein (SP)-A and SP-D are collectins that are present in the epithelial lining fluid of the lung. SP-A interacts with viruses, bacteria and fungi. Furthermore, SP-A binds to various other inhaled glycoconjugates. SP-A receptors on phagocytic cells have been described that are important to ensure rapid pathogen clearance. This innate defence system of the lung may be ...
AbstractCollectins are carbohydrate binding proteins that are implicated in innate host defense. The...
Hydrophilic lung surfactant proteins have emerged as key immunomodulators aimed at recognition and c...
Background: Monomers of the collectin surfactant associated protein-A (SP-A) are arranged in trimers...
AbstractThe lung is an organ with a large inner surface that is continuously in contact with the env...
Surfactant protein A (SP-A) is a large multimeric protein found in the airways and alveoli of the lu...
AbstractSurfactant protein D (SP-D) is considered to play an important role in innate immunity in th...
Abstract: The lung surfactant proteins A and D (SP-A and SP-D) are collectins composed of C-type lec...
AbstractSurfactant protein A (SP-A) is a highly ordered, oligomeric glycoprotein that is secreted in...
AbstractLipopolysaccharide (LPS) induction of TNF-α release is a central event in the pathophysiolog...
Pulmonary surfactant is a mixture of lipids and proteins that covers alveolar surfaces and keeps alv...
This review is focused on the evolution and function of alveolar proteins. The lung faces physical a...
This review is focused on the evolution and function of alveolar proteins. The lung faces physical a...
Lung surfactant proteins A and D belong to a group of soluble humoral pattern recognition receptors,...
Surfactant proteins, SP-A and SP-D, are collagen-containing C-type (calcium dependent) lectins calle...
AbstractSurfactant protein A (SP-A) has been shown to bind to and regulate the functions of both alv...
AbstractCollectins are carbohydrate binding proteins that are implicated in innate host defense. The...
Hydrophilic lung surfactant proteins have emerged as key immunomodulators aimed at recognition and c...
Background: Monomers of the collectin surfactant associated protein-A (SP-A) are arranged in trimers...
AbstractThe lung is an organ with a large inner surface that is continuously in contact with the env...
Surfactant protein A (SP-A) is a large multimeric protein found in the airways and alveoli of the lu...
AbstractSurfactant protein D (SP-D) is considered to play an important role in innate immunity in th...
Abstract: The lung surfactant proteins A and D (SP-A and SP-D) are collectins composed of C-type lec...
AbstractSurfactant protein A (SP-A) is a highly ordered, oligomeric glycoprotein that is secreted in...
AbstractLipopolysaccharide (LPS) induction of TNF-α release is a central event in the pathophysiolog...
Pulmonary surfactant is a mixture of lipids and proteins that covers alveolar surfaces and keeps alv...
This review is focused on the evolution and function of alveolar proteins. The lung faces physical a...
This review is focused on the evolution and function of alveolar proteins. The lung faces physical a...
Lung surfactant proteins A and D belong to a group of soluble humoral pattern recognition receptors,...
Surfactant proteins, SP-A and SP-D, are collagen-containing C-type (calcium dependent) lectins calle...
AbstractSurfactant protein A (SP-A) has been shown to bind to and regulate the functions of both alv...
AbstractCollectins are carbohydrate binding proteins that are implicated in innate host defense. The...
Hydrophilic lung surfactant proteins have emerged as key immunomodulators aimed at recognition and c...
Background: Monomers of the collectin surfactant associated protein-A (SP-A) are arranged in trimers...