0504: Isolated elevation of cardiac troponin is associated with better prognosis of non-ST segment elevation myocardial infarction

PurposeWe sought to evaluate the effect of isolated elevation of cTn on short-term outcomes of NSTE-MIMethodsFrom Oct 2010 to Oct 2013, 3799 patients with NSTE-MI were enrolled on a national multicenter registry. These patients were divided in 2 groups: BM+: elevation of cTn and other biomarkers of myocardial injury (n=2445); BM-: elevation of cTn without rise in the other biomarkers (n=948).The endpoints included in-hospital all-cause mortality and a composite endpoint of death, re-infarction, heart failure (Killip class >2) and resuscitated cardiac arrest during hospitalization. Logistic regression modelling was used to compute adjusted odds ratio of death and of the composite endpoint.ResultsThe BM- patients were younger (66±12 vs. 68±13, p<0.001), more likely to have undergone previous percutaneous coronary intervention (18.6% vs. 15.1%, p=0.013) and had higher baseline values of low-density lipoprotein-cholesterol (114±39 vs. 111±39, p=0.03). Multivessel disease was more frequent in BM+ patients (58.1% vs. 53.5%, p=0.026). Patients with BM- had lower incidence of heart failure (8.4% vs. 20.8% with Killip class >1, p<0.001), left ventricular dysfunction (10.4% vs. 18.4% with left ventricular ejection fraction <40%, p<0.001) and the composite endpoint (5.1% vs. 11.9%, p<0.001). In-hospital all-cause mortality was more common in those BM+ (3.0% vs. 0.7%, p