AbstractRats bearing the Yoshida AH-130 ascites hepatoma showed an increased expression of both uncoupling protein-2 (UCP2) (two-fold) and UCP3 (three- to four-fold) in skeletal muscle (both soleus and gastrocnemius). The increase in mRNA content was associated with increased circulating concentrations of fatty acids (two-fold), triglyceride (two-fold) and cholesterol (1.9-fold). Administration of nicotinic acid to tumor-bearing rats abolishes the hyperlipidemic increase associated with tumor burden. The vitamin treatment also resulted in a decreased UCP3 gene expression in soleus muscle but not in gastrocnemius. It is concluded that circulating fatty acids may be involved in the regulation of UCP3 gene expression in aerobic muscles during ...
Brown adipose tissue and skeletal muscle are known to be important sites for nonshivering thermogene...
The recently discovered uncoupling protein 3 (UCP3) is highly homologous to the mitochondrialinner m...
International audienceCardiolipin (CL) content accumulation leads to an increase in energy wasting i...
AbstractRats bearing the Yoshida AH-130 ascites hepatoma showed an increased expression of both unco...
AbstractImplantation of a fast growing tumour to mice (Lewis lung carcinoma) resulted in a clear cac...
AbstractRats bearing the Yoshida AH-130 ascites hepatoma showed an increased expression of both unco...
The abnormalities of lipid metabolism observed in cancer cachexia may be induced by a lipid-mobilizi...
AbstractUCP3 has been postulated to function in the defense against lipid-induced oxidative muscle d...
UCP3 has been postulated to function in the defense against lipid-induced oxidative muscle damage (l...
Muscle wasting in experimental cancer cachexia has been associated with increased ubiquitin proteaso...
AbstractPhysiological and pathological states that are associated with elevated plasma fatty acids (...
Cachexia is a devastating muscle-wasting syndrome that occurs in patients who have chronic diseases....
SummaryCancer-associated cachexia (CAC) is a wasting syndrome characterized by systemic inflammation...
Alterations in amino acid and protein metabolism particularly in skeletal muscle are a key feature o...
AbstractSince the discovery of the new members of the UCP (uncoupling protein) family, UCP2 and UCP3...
Brown adipose tissue and skeletal muscle are known to be important sites for nonshivering thermogene...
The recently discovered uncoupling protein 3 (UCP3) is highly homologous to the mitochondrialinner m...
International audienceCardiolipin (CL) content accumulation leads to an increase in energy wasting i...
AbstractRats bearing the Yoshida AH-130 ascites hepatoma showed an increased expression of both unco...
AbstractImplantation of a fast growing tumour to mice (Lewis lung carcinoma) resulted in a clear cac...
AbstractRats bearing the Yoshida AH-130 ascites hepatoma showed an increased expression of both unco...
The abnormalities of lipid metabolism observed in cancer cachexia may be induced by a lipid-mobilizi...
AbstractUCP3 has been postulated to function in the defense against lipid-induced oxidative muscle d...
UCP3 has been postulated to function in the defense against lipid-induced oxidative muscle damage (l...
Muscle wasting in experimental cancer cachexia has been associated with increased ubiquitin proteaso...
AbstractPhysiological and pathological states that are associated with elevated plasma fatty acids (...
Cachexia is a devastating muscle-wasting syndrome that occurs in patients who have chronic diseases....
SummaryCancer-associated cachexia (CAC) is a wasting syndrome characterized by systemic inflammation...
Alterations in amino acid and protein metabolism particularly in skeletal muscle are a key feature o...
AbstractSince the discovery of the new members of the UCP (uncoupling protein) family, UCP2 and UCP3...
Brown adipose tissue and skeletal muscle are known to be important sites for nonshivering thermogene...
The recently discovered uncoupling protein 3 (UCP3) is highly homologous to the mitochondrialinner m...
International audienceCardiolipin (CL) content accumulation leads to an increase in energy wasting i...