Long-term results of children operated for hypoplastic left heart syndrome in Children's Heart Centre

Vojtovič, P.
Tláskal, T.
Gebauer, R.
Reich, O.
Chaloupecký, V.
Tomek, V.
Krupičková, S.
Matějka, T.
Hecht, P.
Janoušek, J.

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Publication date

December 2014

DOI

10.1016/j.crvasa.2014.07.006

Publisher

The Czech Society of Cardiology. Published by Elsevier Sp. z o.o.

ISSN

0010-8650

Abstract

AbstractIntroductionHypoplastic left heart syndrome (HLHS), one of the most serious congenital heart defects, can be surgically paliated using 3 subsequent stages. Long-term results of this approach are reviewed in this study.MethodsFifty-two consecutive patients (pts.) operated for HLHS from 1999 to 2012 were evaluated retrospectively.ResultsNorwood stage I operation was performed at the median age of 6.5 days with a total mortality of 19%. Significant risk factor for death was lower weight at surgery (Cox proportional risk per 1g increase=0.997, CI 0.995–0.990, P<0.001). Between stages I and II, 15 catheter/surgical reintervention had to be carried out in 13 pts. (aortic arch narrowing in 10/13). Forty-two pts. underwent stage II operatio...