Autophagy, a process for recycling cellular constituents, is normally associated with cell survival and is thought to be beneficial for tumor maintenance. However, in this issue of Cancer Cell, Lamy and colleagues report that multiple myeloma utilizes caspase-10 to restrain autophagy and undergoes autophagic cell death upon its removal or inhibition
Over the past two decades, the natural history of multiple myeloma (MM) has evolved dramatically, ow...
Over the past two decades, the natural history of multiple myeloma (MM) has evolved dramatically, ow...
SummaryDefective apoptosis renders immortalized epithelial cells highly tumorigenic, but how this is...
Autophagy, a process for recycling cellular constituents, is normally associated with cell survival ...
Autophagy, a process for recycling cellular constituents, is normally associated with cell survival ...
SummaryWe performed a loss-of-function RNA interference screen to define therapeutic targets in mult...
SummaryWe performed a loss-of-function RNA interference screen to define therapeutic targets in mult...
Autophagy is an intracellular self-degradative process that balances cell energy source and regulate...
Multiple myeloma (MM) is a plasma cell cancer characterized by sustained endoplasmic reticulum (ER) ...
Multiple myeloma (MM) is a plasma cell cancer characterized by sustained endoplasmic reticulum (ER) ...
OBJECTIVE: To determine whether the Unfolded Protein Response (UPR) sensors (PERK, ATF6 and IRE-1) c...
To determine whether the Unfolded Protein Response (UPR) sensors (PERK, ATF6 and IRE-1) can be targe...
To determine whether the Unfolded Protein Response (UPR) sensors (PERK, ATF6 and IRE-1) can be targe...
Autophagy is an intracellular self-degradative process that balances cell energy source and regulate...
Multiple myeloma (MM) is a tumor of plasma cells (PCs). Due to the intense immunoglobulin secretion,...
Over the past two decades, the natural history of multiple myeloma (MM) has evolved dramatically, ow...
Over the past two decades, the natural history of multiple myeloma (MM) has evolved dramatically, ow...
SummaryDefective apoptosis renders immortalized epithelial cells highly tumorigenic, but how this is...
Autophagy, a process for recycling cellular constituents, is normally associated with cell survival ...
Autophagy, a process for recycling cellular constituents, is normally associated with cell survival ...
SummaryWe performed a loss-of-function RNA interference screen to define therapeutic targets in mult...
SummaryWe performed a loss-of-function RNA interference screen to define therapeutic targets in mult...
Autophagy is an intracellular self-degradative process that balances cell energy source and regulate...
Multiple myeloma (MM) is a plasma cell cancer characterized by sustained endoplasmic reticulum (ER) ...
Multiple myeloma (MM) is a plasma cell cancer characterized by sustained endoplasmic reticulum (ER) ...
OBJECTIVE: To determine whether the Unfolded Protein Response (UPR) sensors (PERK, ATF6 and IRE-1) c...
To determine whether the Unfolded Protein Response (UPR) sensors (PERK, ATF6 and IRE-1) can be targe...
To determine whether the Unfolded Protein Response (UPR) sensors (PERK, ATF6 and IRE-1) can be targe...
Autophagy is an intracellular self-degradative process that balances cell energy source and regulate...
Multiple myeloma (MM) is a tumor of plasma cells (PCs). Due to the intense immunoglobulin secretion,...
Over the past two decades, the natural history of multiple myeloma (MM) has evolved dramatically, ow...
Over the past two decades, the natural history of multiple myeloma (MM) has evolved dramatically, ow...
SummaryDefective apoptosis renders immortalized epithelial cells highly tumorigenic, but how this is...