Pulmonary Langerhans cell histiocytosis concurrent with bronchial hyperresponsiveness on a nonsmoker adult presenting with spontaneous pneumothorax
- Suttithawil, Wudthichai
- Lertpradit, Pattanasak
- Yenarkarn, Panuch
- Techapaitoon, Satien
- Huntrakoon, Manop
- Ploysongsang, Yongyudh
DOIAbstract
SummaryWe report a nonsmoker adult with histologically proven pulmonary Langerhans cell histiocytosis (PLCH) with bronchial hyperresponsiveness (BHR) presenting with spontaneous pneumothorax. An 18-year-old, nonsmoker student had shortness of breath for a decade. PFTs and lung volume study (obtained one month post-operation) showed a mild obstructive airway with bronchodilator response and a decreased DLco with a positive methacholine challenge test (PC20<8mg/ml). Chest radiograph revealed right-sided pneumothorax and diffuse reticular infiltrates. HRCT revealed scattered, thin-walled lung cysts in all lobes without sparing of the costophrenic angles. The patient underwent a thoracotomy for wedge resection and the diagnosis of PLCH was conf...
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