AbstractSREBPs are transcriptional activators central to cholesterol homeostasis. Recent work has shown that a two-step cleavage of membrane-bound SREBPs frees them to enter the nucleus. An activator of the first, sterol-regulated proteolysis step has also been identified
The regulatory pool of cholesterol is located in the endoplasmic reticulum (ER) and is key to how ma...
ate cholesterol synthesis and uptake. This system maintains cholesterol homeostasis by increasing ch...
Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regul...
AbstractSREBPs are transcriptional activators central to cholesterol homeostasis. Recent work has sh...
AbstractTranscriptional regulation and membrane traffic have traditionally been quite separate field...
AbstractThree new studies have wide implications for cholesterol homeostasis, identifying a novel me...
AbstractCholesterol homeostasis in animal cells is achieved by regulated cleavage of membrane-bound ...
AbstractThrough expression cloning we have isolated a cDNA-encoding SREBP cleavage–activating protei...
Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesi...
SummaryThis paper describes a convergent mechanism for the feedback control of cholesterol synthesis...
SummaryThe sterol regulatory element binding protein (SREBP) family of transcription factors control...
Presents Cholesterol homeostasis in mammalian cells is regulated at the level of transcription throu...
SREBP complex is incorporated into COPII-coated vesicles that bud from the ER and carry the SREBPs t...
Cholesterol regulates activation of sterol regulatory element-binding protein (SREBP) through a clas...
AbstractCholesterol homeostasis is established by a complex of three proteins, one of which contains...
The regulatory pool of cholesterol is located in the endoplasmic reticulum (ER) and is key to how ma...
ate cholesterol synthesis and uptake. This system maintains cholesterol homeostasis by increasing ch...
Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regul...
AbstractSREBPs are transcriptional activators central to cholesterol homeostasis. Recent work has sh...
AbstractTranscriptional regulation and membrane traffic have traditionally been quite separate field...
AbstractThree new studies have wide implications for cholesterol homeostasis, identifying a novel me...
AbstractCholesterol homeostasis in animal cells is achieved by regulated cleavage of membrane-bound ...
AbstractThrough expression cloning we have isolated a cDNA-encoding SREBP cleavage–activating protei...
Sterol regulatory element-binding protein (SREBP) transcription factors regulate cellular lipogenesi...
SummaryThis paper describes a convergent mechanism for the feedback control of cholesterol synthesis...
SummaryThe sterol regulatory element binding protein (SREBP) family of transcription factors control...
Presents Cholesterol homeostasis in mammalian cells is regulated at the level of transcription throu...
SREBP complex is incorporated into COPII-coated vesicles that bud from the ER and carry the SREBPs t...
Cholesterol regulates activation of sterol regulatory element-binding protein (SREBP) through a clas...
AbstractCholesterol homeostasis is established by a complex of three proteins, one of which contains...
The regulatory pool of cholesterol is located in the endoplasmic reticulum (ER) and is key to how ma...
ate cholesterol synthesis and uptake. This system maintains cholesterol homeostasis by increasing ch...
Sterol regulatory element binding proteins (SREBPs) are a family of transcription factors that regul...
DOI
Add to ORKG