Mössbauer spectroscopy of haemoglobins Study of the relationship of Fe2+ electronic and molecular structure of the active site

AbstractHuman normal, adult and foetal oxyhaemoglobins and oxyhaemoglobins from leukaemic patients were studied, by Mössbauer spectroscopy. The estimations of quadrupole splitting ΔEQ and isomer shift δ allow one to distinguish between adult, foetal and leukaemic oxyhaemoglobins. The differences in the Fe2+ electronic structure and active site molecular structure of foetal and leukaemic oxyhaemoglobins were analyzed