AbstractReplicative DNA polymerases are highly processive enzymes that polymerize thousands of nucleotides without dissociating from the DNA template. The recently determined structure of the Escherichia coli bacteriophage T7 DNA polymerase suggests a unique mechanism that underlies processivity, and this mechanism may generalize to other replicative polymerases
In all known cellular organisms, from the smallest bacteria to the tallest of trees, DNA stores the ...
Due to the limited processivity of replicative DNA polymerases (replicases), as well as to their inc...
DNA replication efficiency is dictated by DNA polymerases (pol) and their associated proteins. The r...
AbstractReplicative DNA polymerases are highly processive enzymes that polymerize thousands of nucle...
AbstractThe structure of the DNA polymerase from bacteriophage φ29 (Kamtekar et al., 2004), which us...
During DNA replication replicative polymerases move in discrete mechanical steps along the DNA templ...
DNA polymerases are involved in different cellular events, including genome replication and DNA r...
Replicative holoenzymes exhibit rapid and processive primer extension DNA synthesis, but inefficient...
A single copy of bacteriophage T7 DNA polymerase and DNA helicase advance the replication fork with ...
A single copy of bacteriophage T7 DNA polymerase and DNA helicase advance the replication fork with ...
A single copy of bacteriophage T7 DNA polymerase and DNA helicase advance the replication fork with ...
A single copy of bacteriophage T7 DNA polymerase and DNA helicase advance the replication fork with ...
not initiate new chains. In addition, it was known that there were three different DNA polymerases i...
Proofreading by replicative DNA polymerases is a fundamental mechanism ensuring DNA replication fide...
Proofreading by replicative DNA polymerases is a fundamental mechanism ensuring DNA replication fide...
In all known cellular organisms, from the smallest bacteria to the tallest of trees, DNA stores the ...
Due to the limited processivity of replicative DNA polymerases (replicases), as well as to their inc...
DNA replication efficiency is dictated by DNA polymerases (pol) and their associated proteins. The r...
AbstractReplicative DNA polymerases are highly processive enzymes that polymerize thousands of nucle...
AbstractThe structure of the DNA polymerase from bacteriophage φ29 (Kamtekar et al., 2004), which us...
During DNA replication replicative polymerases move in discrete mechanical steps along the DNA templ...
DNA polymerases are involved in different cellular events, including genome replication and DNA r...
Replicative holoenzymes exhibit rapid and processive primer extension DNA synthesis, but inefficient...
A single copy of bacteriophage T7 DNA polymerase and DNA helicase advance the replication fork with ...
A single copy of bacteriophage T7 DNA polymerase and DNA helicase advance the replication fork with ...
A single copy of bacteriophage T7 DNA polymerase and DNA helicase advance the replication fork with ...
A single copy of bacteriophage T7 DNA polymerase and DNA helicase advance the replication fork with ...
not initiate new chains. In addition, it was known that there were three different DNA polymerases i...
Proofreading by replicative DNA polymerases is a fundamental mechanism ensuring DNA replication fide...
Proofreading by replicative DNA polymerases is a fundamental mechanism ensuring DNA replication fide...
In all known cellular organisms, from the smallest bacteria to the tallest of trees, DNA stores the ...
Due to the limited processivity of replicative DNA polymerases (replicases), as well as to their inc...
DNA replication efficiency is dictated by DNA polymerases (pol) and their associated proteins. The r...