AbstractCodon-specific incorporation of noncoded amino acids into proteins can diversify the genetic code. Now, in both E. coli and S. cerevisiae, iterative rounds of selection can be used to isolate aminoacyl-tRNA synthetases that aminoacylate suppressor tRNAs with noncoded amino acids
AbstractThe genetic code can be interpreted during translation as 21 amino acids and three terminati...
Genetic code expansion (GCE) has become a central topic of synthetic biology. GCE relies on engineer...
Genetic code expansion (GCE) has become a central topic of synthetic biology. GCE relies on engineer...
AbstractCodon-specific incorporation of noncoded amino acids into proteins can diversify the genetic...
AbstractBackground: Chemically aminoacylated suppressor tRNAs have previously been used in vitro to ...
There have been considerable advancements in the incorporation of noncanonical amino acids (ncAA) in...
AbstractOver 300 amino acids are found in proteins in nature, yet typically only 20 are genetically ...
Genetic incorporation of noncanonical amino acids (ncAAs) has become a powerful tool to enhance exis...
AbstractThe addition of new and versatile chemical and biological properties to proteins pursued thr...
Over the last decade, the ability to genetically encode unnatural amino acids (UAAs) has evolved rap...
Aminoacyl-tRNAs (aa-tRNAs) are simple molecules with a single purpose—to serve as substrates for tra...
By using a directed evolution approach, we have identified aminoacyl-tRNA synthetase variants with s...
AbstractNew studies are challenging the invariance of the building blocks of naturally occurring pro...
Proteins in nature are synthesized from a conservative set of 20 canonical amino acids, limiting the...
Expansion of the genetic code through engineering of the translation machinery has vastly increased ...
AbstractThe genetic code can be interpreted during translation as 21 amino acids and three terminati...
Genetic code expansion (GCE) has become a central topic of synthetic biology. GCE relies on engineer...
Genetic code expansion (GCE) has become a central topic of synthetic biology. GCE relies on engineer...
AbstractCodon-specific incorporation of noncoded amino acids into proteins can diversify the genetic...
AbstractBackground: Chemically aminoacylated suppressor tRNAs have previously been used in vitro to ...
There have been considerable advancements in the incorporation of noncanonical amino acids (ncAA) in...
AbstractOver 300 amino acids are found in proteins in nature, yet typically only 20 are genetically ...
Genetic incorporation of noncanonical amino acids (ncAAs) has become a powerful tool to enhance exis...
AbstractThe addition of new and versatile chemical and biological properties to proteins pursued thr...
Over the last decade, the ability to genetically encode unnatural amino acids (UAAs) has evolved rap...
Aminoacyl-tRNAs (aa-tRNAs) are simple molecules with a single purpose—to serve as substrates for tra...
By using a directed evolution approach, we have identified aminoacyl-tRNA synthetase variants with s...
AbstractNew studies are challenging the invariance of the building blocks of naturally occurring pro...
Proteins in nature are synthesized from a conservative set of 20 canonical amino acids, limiting the...
Expansion of the genetic code through engineering of the translation machinery has vastly increased ...
AbstractThe genetic code can be interpreted during translation as 21 amino acids and three terminati...
Genetic code expansion (GCE) has become a central topic of synthetic biology. GCE relies on engineer...
Genetic code expansion (GCE) has become a central topic of synthetic biology. GCE relies on engineer...
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