Retroviral restriction is a complex phenomenon that, despite remarkable recent progress, is far from being well understood. In this Preview, we introduce an insightful study by Yang et al. that represents the first attempt to identify the global determinants of retroviral repression in pluripotent mammalian cells
Almost half of our genome is occupied by transposable elements. Although most of them are inactive, ...
The tight regulation of protein expression is critical for the survival of mammalian cells, providin...
There are myriad mechanisms that regulate gene expression. New variations on the traditional themes ...
Retroviral restriction is a complex phenomenon that, despite remarkable recent progress, is far from...
Embryonic stem (ES) cells potently repress retroviral infection through transcriptional silencing of...
SummaryEmbryonic cells transcriptionally repress the expression of endogenous and exogenous retroele...
Embryonic cells silence transcription by retroviruses, but how do they recognize virus DNA? In this ...
Embryonic cells transcriptionally repress the expression of endogenous and exogenous retroelements. ...
In this issue of Cell Host & Microbe, OhAinle et al., 2008 report that APOBEC3H, a potent innate ret...
Background Retroviral DNAs are profoundly silenced at the transcriptional level in embryonic cell ty...
peer reviewedBoth exogenous and endogenous retroviruses have long been studied in mice, and some of ...
While mammalian cells provide many of the molecules and machinery required by retroviruses to succes...
SummaryTo prevent insertional mutagenesis arising from retroviral reactivation, cells of embryonic o...
SummaryEmbryonic stem cells (ESCs) repress the expression of exogenous proviruses and endogenous ret...
Retroelements, constituting about 50% of the human genome, both contribute to its evolution and thre...
Almost half of our genome is occupied by transposable elements. Although most of them are inactive, ...
The tight regulation of protein expression is critical for the survival of mammalian cells, providin...
There are myriad mechanisms that regulate gene expression. New variations on the traditional themes ...
Retroviral restriction is a complex phenomenon that, despite remarkable recent progress, is far from...
Embryonic stem (ES) cells potently repress retroviral infection through transcriptional silencing of...
SummaryEmbryonic cells transcriptionally repress the expression of endogenous and exogenous retroele...
Embryonic cells silence transcription by retroviruses, but how do they recognize virus DNA? In this ...
Embryonic cells transcriptionally repress the expression of endogenous and exogenous retroelements. ...
In this issue of Cell Host & Microbe, OhAinle et al., 2008 report that APOBEC3H, a potent innate ret...
Background Retroviral DNAs are profoundly silenced at the transcriptional level in embryonic cell ty...
peer reviewedBoth exogenous and endogenous retroviruses have long been studied in mice, and some of ...
While mammalian cells provide many of the molecules and machinery required by retroviruses to succes...
SummaryTo prevent insertional mutagenesis arising from retroviral reactivation, cells of embryonic o...
SummaryEmbryonic stem cells (ESCs) repress the expression of exogenous proviruses and endogenous ret...
Retroelements, constituting about 50% of the human genome, both contribute to its evolution and thre...
Almost half of our genome is occupied by transposable elements. Although most of them are inactive, ...
The tight regulation of protein expression is critical for the survival of mammalian cells, providin...
There are myriad mechanisms that regulate gene expression. New variations on the traditional themes ...
DOI
Add to ORKG