A protective effect of intravenous diltiazem pretreatment on transmural histologic damage in ischemic hearts of 30 pigs was determined morphometrically. The pig hearts were rendered ischemic by ligation of the distal left anterior descending coronary artery for 20, 40 and 120 minutes in separate experiments. Heart rate, left ventricular systolic pressure and systemic diastolic pressure decreased slightly during 40 minutes of occlusion, and then recovered to control levels. However, there were no significant differences between control and diltiazem-treated groups. Blood flow, measured by the microsphere technique, was uniformly absent in the ischemic areas in both control and diltiazem-treated hearts. In the few cell layers immediately bene...
Diltiazem may provide a protective effect to ischemic and reperfused myocardium through preservation...
The effect of diltiazem vs. saline was studied in a conscious canine model of coronary thrombosis. D...
Calcium channel antagonists have been shown to blunt maximal coronary flow after brief coronary occl...
A protective effect of intravenous diltiazem pretreatment on transmural histologic damage in ischemi...
Diltiazem was evaluated for its ability to reduce the extent of ischemic injury in isolated blood-pe...
The calcium channel blocking agent, diltiazem, improves ischemia-induced conduction delays in the ca...
The protective effects of diltiazem were studied in isolated perfused rat hearts after 10, 20 and 30...
AbstractProlonged depression of segmental systolic thickening after brief coronary artery occlusion ...
AbstractThis study was designed to investigate whether intracoronary diltiazem given before reperfus...
AbstractThe effect of intracoronary diltiazem, EGTA (ethylenebis-(β-aminomethylether)-N,N′-tetraacet...
Concomitant use of pharmacologie agents may be required for maximal salvage of ischemic myocardium b...
The effect of diltiazem, a calcium channel blocking agent, on anoxic injury was studied in isolated ...
We have recently demonstrated that calcium channel blockers can protect the ischemic myoca.rdium at ...
The effects of the calcium antagonist, diltiazem, on myocardial injury during ischemia and reperfusi...
AbstractObjectives. This study was defined as a pilot investigation of the usefulness and safety of ...
Diltiazem may provide a protective effect to ischemic and reperfused myocardium through preservation...
The effect of diltiazem vs. saline was studied in a conscious canine model of coronary thrombosis. D...
Calcium channel antagonists have been shown to blunt maximal coronary flow after brief coronary occl...
A protective effect of intravenous diltiazem pretreatment on transmural histologic damage in ischemi...
Diltiazem was evaluated for its ability to reduce the extent of ischemic injury in isolated blood-pe...
The calcium channel blocking agent, diltiazem, improves ischemia-induced conduction delays in the ca...
The protective effects of diltiazem were studied in isolated perfused rat hearts after 10, 20 and 30...
AbstractProlonged depression of segmental systolic thickening after brief coronary artery occlusion ...
AbstractThis study was designed to investigate whether intracoronary diltiazem given before reperfus...
AbstractThe effect of intracoronary diltiazem, EGTA (ethylenebis-(β-aminomethylether)-N,N′-tetraacet...
Concomitant use of pharmacologie agents may be required for maximal salvage of ischemic myocardium b...
The effect of diltiazem, a calcium channel blocking agent, on anoxic injury was studied in isolated ...
We have recently demonstrated that calcium channel blockers can protect the ischemic myoca.rdium at ...
The effects of the calcium antagonist, diltiazem, on myocardial injury during ischemia and reperfusi...
AbstractObjectives. This study was defined as a pilot investigation of the usefulness and safety of ...
Diltiazem may provide a protective effect to ischemic and reperfused myocardium through preservation...
The effect of diltiazem vs. saline was studied in a conscious canine model of coronary thrombosis. D...
Calcium channel antagonists have been shown to blunt maximal coronary flow after brief coronary occl...