AbstractSR proteins serve multiple roles in the posttranscriptional control of gene expression, including as regulators of alternative splicing. In this issue of Cell, Xu et al. (2005) demonstrate that a heart-specific knockout of one SR protein, ASF/SF2, produces cardiomyopathy and misregulation of specific alternative splicing events during early postnatal development
Summary: The serine/arginine-rich (SR) family of splicing factors plays important roles in mRNA spli...
<div><p>Members of the CUG-BP, Elav-like family (CELF) regulate alternative splicing in the heart. I...
Members of the CUG-BP, Elav-like family (CELF) regulate alternative splicing in the heart. In MHC-CE...
AbstractThe transition from juvenile to adult life is accompanied by programmed remodeling in many t...
Advancements in genomics, bioinformatics, and genome editing have uncovered new dimensions in gene r...
Alternative splicing of primary RNA transcripts greatly diversifies the amount of proteins encoded b...
Alternative splicing is the main driver of protein diversity and allows the production of different ...
During postnatal development the heart undergoes a rapid and dramatic transition to adult function t...
During cardiac development and pathological remodeling, there is a transcriptome maturation and remo...
RNA splicing represents a post-transcriptional mechanism to generate multiple functional RNAs or pro...
The role of alternative splicing in self-renewal, pluripotency and tissue lineage specification of h...
Pre-mRNA splicing is an important biological process that allows production of multiple proteins...
Proper RNA splicing is increasingly recognized as an important contributor to normal cardiac functio...
Driven by rapidly evolving technologies in next-generation sequencing, alternative splicing has emer...
The role of alternative splicing in self-renewal, pluripotency and tissue lineage specification of h...
Summary: The serine/arginine-rich (SR) family of splicing factors plays important roles in mRNA spli...
<div><p>Members of the CUG-BP, Elav-like family (CELF) regulate alternative splicing in the heart. I...
Members of the CUG-BP, Elav-like family (CELF) regulate alternative splicing in the heart. In MHC-CE...
AbstractThe transition from juvenile to adult life is accompanied by programmed remodeling in many t...
Advancements in genomics, bioinformatics, and genome editing have uncovered new dimensions in gene r...
Alternative splicing of primary RNA transcripts greatly diversifies the amount of proteins encoded b...
Alternative splicing is the main driver of protein diversity and allows the production of different ...
During postnatal development the heart undergoes a rapid and dramatic transition to adult function t...
During cardiac development and pathological remodeling, there is a transcriptome maturation and remo...
RNA splicing represents a post-transcriptional mechanism to generate multiple functional RNAs or pro...
The role of alternative splicing in self-renewal, pluripotency and tissue lineage specification of h...
Pre-mRNA splicing is an important biological process that allows production of multiple proteins...
Proper RNA splicing is increasingly recognized as an important contributor to normal cardiac functio...
Driven by rapidly evolving technologies in next-generation sequencing, alternative splicing has emer...
The role of alternative splicing in self-renewal, pluripotency and tissue lineage specification of h...
Summary: The serine/arginine-rich (SR) family of splicing factors plays important roles in mRNA spli...
<div><p>Members of the CUG-BP, Elav-like family (CELF) regulate alternative splicing in the heart. I...
Members of the CUG-BP, Elav-like family (CELF) regulate alternative splicing in the heart. In MHC-CE...
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