The destruction of pluripotent stem cell-derived grafts by the host immune system presents a significant barrier to clinical translation of cell therapies. Pearl et al. (2011) report in this issue of Cell Stem Cell that a brief, nontoxic immunosuppressive regimen, achieved by blockade of leucocyte costimulatory pathways, may overcome this problem
The recent generation of induced pluripotent stem (iPS) cells from adult human somatic cells has int...
Immune rejection is a critical barrier to successful organ transplantation and stem cell therapies. ...
Abstract: One aim of stem cell-based therapy is to utilize pluripotent stem cells (PSCs) as a supple...
The destruction of pluripotent stem cell-derived grafts by the host immune system presents a signifi...
SummaryEmbryonic stem cells (ESCs) are an attractive source for tissue regeneration and repair thera...
Morizane et al. (2013) show that donor-matched differentiated derivatives of induced pluripotent ste...
Stem cell transplantation consists in the introduction of stem cells or derived products in a diseas...
Abstract: The central goal of regenerative medicine is to replace damaged or diseased tissue with ce...
SummaryHuman embryonic stem cells (hESCs) hold great promise for cell therapy as a source of diverse...
The use of human embryonic stem cells (hESCs) for regenerative medicine currently faces several hurd...
The shortage of donors for organ transplantation and also to treat degenerative diseases has led to ...
The central goal of regenerative medicine is to replace damaged or diseased tissue with cells that i...
Resident pools of somatic stem cells in many organs are responsible for tissue maintenance and repai...
Implantation of human embryonic stem cells (hES), derived progenitors or mature cells derived from h...
SummaryThe proliferative capacity of pluripotent stem cells and their progeny brings a unique aspect...
The recent generation of induced pluripotent stem (iPS) cells from adult human somatic cells has int...
Immune rejection is a critical barrier to successful organ transplantation and stem cell therapies. ...
Abstract: One aim of stem cell-based therapy is to utilize pluripotent stem cells (PSCs) as a supple...
The destruction of pluripotent stem cell-derived grafts by the host immune system presents a signifi...
SummaryEmbryonic stem cells (ESCs) are an attractive source for tissue regeneration and repair thera...
Morizane et al. (2013) show that donor-matched differentiated derivatives of induced pluripotent ste...
Stem cell transplantation consists in the introduction of stem cells or derived products in a diseas...
Abstract: The central goal of regenerative medicine is to replace damaged or diseased tissue with ce...
SummaryHuman embryonic stem cells (hESCs) hold great promise for cell therapy as a source of diverse...
The use of human embryonic stem cells (hESCs) for regenerative medicine currently faces several hurd...
The shortage of donors for organ transplantation and also to treat degenerative diseases has led to ...
The central goal of regenerative medicine is to replace damaged or diseased tissue with cells that i...
Resident pools of somatic stem cells in many organs are responsible for tissue maintenance and repai...
Implantation of human embryonic stem cells (hES), derived progenitors or mature cells derived from h...
SummaryThe proliferative capacity of pluripotent stem cells and their progeny brings a unique aspect...
The recent generation of induced pluripotent stem (iPS) cells from adult human somatic cells has int...
Immune rejection is a critical barrier to successful organ transplantation and stem cell therapies. ...
Abstract: One aim of stem cell-based therapy is to utilize pluripotent stem cells (PSCs) as a supple...
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