Antigen receptor-induced NF-κB activation depends on receptor-proximal and -distal signaling events. Two papers in this issue of Immunity demonstrate that PKC-dependent phosphorylation of CARMA1 is the critical molecular link that controls the activation of the IKK signalosome and NF-κB
Carma-1 is required for B cell receptor-/CD40- and T cell receptor-/CD28-induced B- and T-cell activ...
The Carma1-Bcl10-Malt1 (CBM) complex bridges T-cell receptor (TCR) signalling to the canonical I&kap...
The transcription factor NF-κB plays a key regulatory role in lymphocyte activation and generation o...
SummaryPKC isoforms and CARMA1 play crucial roles in immunoreceptor-dependent NF-κB activation. We t...
Antigen receptor-induced NF-κB activation depends on receptor-proximal and -distal signaling events....
Antigen receptor-induced NF-kappaB activation depends on receptor-proximal and -distal signaling eve...
SummaryCARMA1 mediates T cell receptor (TCR)-induced NF-κB activation. However, how TCR links to CAR...
AbstractLymphocyte activation via antigen receptors initiates adaptive immune responses. Two papers ...
CARMA proteins are scaffold molecules that contain a caspase recruitment domain and a membrane-assoc...
Activation of the transcription factor NF-kB after engagement of the T cell receptor (TCR) is import...
Activation of the NF-kappaB pathway in T cells is required for induction of an adaptive immune respo...
CARMA1 is a lymphocyte-specific member of the membrane-associated guanylate kinase (MAGUK) family of...
CARMA proteins are scaffold molecules that contain a caspase recruitment domain and a membrane-assoc...
The NF-κB signaling pathway is important in the regulation of physiological and malignant hematopoie...
Ligation of antigen receptors (TCR, BCR) on T and B lymphocytes leads to the activation of new trans...
Carma-1 is required for B cell receptor-/CD40- and T cell receptor-/CD28-induced B- and T-cell activ...
The Carma1-Bcl10-Malt1 (CBM) complex bridges T-cell receptor (TCR) signalling to the canonical I&kap...
The transcription factor NF-κB plays a key regulatory role in lymphocyte activation and generation o...
SummaryPKC isoforms and CARMA1 play crucial roles in immunoreceptor-dependent NF-κB activation. We t...
Antigen receptor-induced NF-κB activation depends on receptor-proximal and -distal signaling events....
Antigen receptor-induced NF-kappaB activation depends on receptor-proximal and -distal signaling eve...
SummaryCARMA1 mediates T cell receptor (TCR)-induced NF-κB activation. However, how TCR links to CAR...
AbstractLymphocyte activation via antigen receptors initiates adaptive immune responses. Two papers ...
CARMA proteins are scaffold molecules that contain a caspase recruitment domain and a membrane-assoc...
Activation of the transcription factor NF-kB after engagement of the T cell receptor (TCR) is import...
Activation of the NF-kappaB pathway in T cells is required for induction of an adaptive immune respo...
CARMA1 is a lymphocyte-specific member of the membrane-associated guanylate kinase (MAGUK) family of...
CARMA proteins are scaffold molecules that contain a caspase recruitment domain and a membrane-assoc...
The NF-κB signaling pathway is important in the regulation of physiological and malignant hematopoie...
Ligation of antigen receptors (TCR, BCR) on T and B lymphocytes leads to the activation of new trans...
Carma-1 is required for B cell receptor-/CD40- and T cell receptor-/CD28-induced B- and T-cell activ...
The Carma1-Bcl10-Malt1 (CBM) complex bridges T-cell receptor (TCR) signalling to the canonical I&kap...
The transcription factor NF-κB plays a key regulatory role in lymphocyte activation and generation o...
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