AbstractTwo recent studies illustrate the ability of the Mre11/Rad50 DNA repair complex to bind and connect DNA ends. Specific stimulation of DNA ligase IV-mediated end-joining by Mre11 complexes from S. cerevisiae suggests the possibility of a direct role in nonhomologous end-joining in eukaryotic cells
Summary: The minichromosome maintenance (MCM) helicase physically interacts with the recombination p...
DNA double-strand breaks (DSBs) are the most deleterious damage which cells can encounter. Unrepaire...
In an effort to understand the molecular mechanisms of DNA alkylation repair, I initiated molecular ...
AbstractTwo recent studies illustrate the ability of the Mre11/Rad50 DNA repair complex to bind and ...
The Mre11 complex (Mre11, Rad50 and Xrs2 in Saccharomyces cerevisiae) influences diverse functions i...
SummaryThe MR (Mre11 nuclease and Rad50 ABC ATPase) complex is an evolutionarily conserved sensor fo...
AbstractTo clarify functions of the Mre11/Rad50 (MR) complex in DNA double-strand break repair, we r...
The MR (Mre11 nuclease and Rad50 ABC ATPase) complex is an evolutionarily conserved sensor for DNA d...
textEukaryotic cells repair DNA double-strand breaks (DSBs) through both non-homologous and homologo...
DoctorThe MRN complex composed of Mre11, Rad50, and Nbs1 (Xrs2 in S.cerevisiae) is a sophisticated p...
Maintenance of genomic integrity is essential for the survival of an organism and its ability to pas...
The Mre11–Rad50–Nbs1 (MRN) complex is a central factor in the repair of DNA double‐strand breaks (DS...
Rad50 contains a conserved Zn2+ coordination domain (the Rad50 hook) that functions as a homodimeriz...
AbstractThe Mre11-Rad50-Nbs1 (MRN) complex is a dynamic macromolecular machine that acts in the firs...
In eukaryotes, the repair of DSBs is accomplished through two broadly defined processes: Non-Homolog...
Summary: The minichromosome maintenance (MCM) helicase physically interacts with the recombination p...
DNA double-strand breaks (DSBs) are the most deleterious damage which cells can encounter. Unrepaire...
In an effort to understand the molecular mechanisms of DNA alkylation repair, I initiated molecular ...
AbstractTwo recent studies illustrate the ability of the Mre11/Rad50 DNA repair complex to bind and ...
The Mre11 complex (Mre11, Rad50 and Xrs2 in Saccharomyces cerevisiae) influences diverse functions i...
SummaryThe MR (Mre11 nuclease and Rad50 ABC ATPase) complex is an evolutionarily conserved sensor fo...
AbstractTo clarify functions of the Mre11/Rad50 (MR) complex in DNA double-strand break repair, we r...
The MR (Mre11 nuclease and Rad50 ABC ATPase) complex is an evolutionarily conserved sensor for DNA d...
textEukaryotic cells repair DNA double-strand breaks (DSBs) through both non-homologous and homologo...
DoctorThe MRN complex composed of Mre11, Rad50, and Nbs1 (Xrs2 in S.cerevisiae) is a sophisticated p...
Maintenance of genomic integrity is essential for the survival of an organism and its ability to pas...
The Mre11–Rad50–Nbs1 (MRN) complex is a central factor in the repair of DNA double‐strand breaks (DS...
Rad50 contains a conserved Zn2+ coordination domain (the Rad50 hook) that functions as a homodimeriz...
AbstractThe Mre11-Rad50-Nbs1 (MRN) complex is a dynamic macromolecular machine that acts in the firs...
In eukaryotes, the repair of DSBs is accomplished through two broadly defined processes: Non-Homolog...
Summary: The minichromosome maintenance (MCM) helicase physically interacts with the recombination p...
DNA double-strand breaks (DSBs) are the most deleterious damage which cells can encounter. Unrepaire...
In an effort to understand the molecular mechanisms of DNA alkylation repair, I initiated molecular ...
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