High-resolution melting analysis for the detection of two erythromycin-resistant Bordetella pertussis strains carried by healthy schoolchildren in China
- Zhang, Q.
- Li, M.
- Wang, L.
- Xin, T.
- He, Q.
Publication date
June 2013
DOI Publisher
European Society of Clinical Microbiology and Infectious Diseases. Published by Elsevier Ltd. ISSN
1198-743X Citation count (estimate)
8Abstract
AbstractTwo erythromycin-resistant strains of Bordetella pertussis were isolated from nasopharyngeal specimens of two asymptomatic schoolchildren in China. High-resolution melting and sequencing analyses confirmed the homogeneous A2047G mutation in 23S rRNA genes of the two isolates. High-resolution melting (HRM) analysis is a useful assay for the rapid detection of erythromycin-resistant B. pertussis. The appearance of erythromycin-resistant B. pertussis strains in China is alarming
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