AbstractThe recently reported modest success of the RV144 Thai trial vaccine regimen in preventing HIV-1 acquisition has focused interest on the potential contribution to that protection of vaccine-elicited CD4+ T cell responses. We evaluated the induction of virus-specific CD4+ T cell responses in rhesus monkeys using a series of diverse vaccine vectors. We assessed both the magnitudes and functional profiles of the antigen-specific CD4+ T cells by measuring cytokine production, memory differentiation, and the expression of mucosal homing molecules. We found that DNA prime/recombinant MVA boost immunizations induced particularly high-frequency virus-specific CD4+ T cell responses with polyfunctional repertoires, and these responses were pa...
The goal of an effective AIDS vaccine is to generate immunity that will prevent human immunodeficien...
Live attenuated measles virus is one of the most efficient and safest vaccines available, making it ...
HIV vaccine mediated efficacy, using an expanded live attenuated recombinant varicella virus-vectore...
AbstractThe recently reported modest success of the RV144 Thai trial vaccine regimen in preventing H...
AbstractTo target the HIV CD4i envelope epitope, we primed rhesus macaques with replicating Ad-rhFLS...
International audienceBACKGROUND: Immunization protocols involving priming with DNA and boosting wit...
The RV144 vaccine trial in Thailand demonstrated that an HIV vaccine could prevent infection in huma...
AbstractWe investigated the immunogenicity and efficacy of a bimodal prime/boost vaccine regimen giv...
This is the publisher's version, also available electronically from "http://jvi.asm.org".Cellular im...
AbstractTo identify the most promising vaccine candidates for combinatorial strategies, we compared ...
AbstractRecombinant rhabdovirus vectors expressing human immunodeficiency virus (HIV) and/or simian ...
Live attenuated measles virus is one of the most efficient and safest vaccines available, making it ...
The recombinant canarypox vector, ALVAC-HIV, together with human immunodeficiency virus (HIV) gp120 ...
The quest for an efficacious HIV vaccine has resulted in several clinical trial failures, including ...
The RV144 vaccine trial in Thailand demonstrated that an HIV vaccine could prevent infection in huma...
The goal of an effective AIDS vaccine is to generate immunity that will prevent human immunodeficien...
Live attenuated measles virus is one of the most efficient and safest vaccines available, making it ...
HIV vaccine mediated efficacy, using an expanded live attenuated recombinant varicella virus-vectore...
AbstractThe recently reported modest success of the RV144 Thai trial vaccine regimen in preventing H...
AbstractTo target the HIV CD4i envelope epitope, we primed rhesus macaques with replicating Ad-rhFLS...
International audienceBACKGROUND: Immunization protocols involving priming with DNA and boosting wit...
The RV144 vaccine trial in Thailand demonstrated that an HIV vaccine could prevent infection in huma...
AbstractWe investigated the immunogenicity and efficacy of a bimodal prime/boost vaccine regimen giv...
This is the publisher's version, also available electronically from "http://jvi.asm.org".Cellular im...
AbstractTo identify the most promising vaccine candidates for combinatorial strategies, we compared ...
AbstractRecombinant rhabdovirus vectors expressing human immunodeficiency virus (HIV) and/or simian ...
Live attenuated measles virus is one of the most efficient and safest vaccines available, making it ...
The recombinant canarypox vector, ALVAC-HIV, together with human immunodeficiency virus (HIV) gp120 ...
The quest for an efficacious HIV vaccine has resulted in several clinical trial failures, including ...
The RV144 vaccine trial in Thailand demonstrated that an HIV vaccine could prevent infection in huma...
The goal of an effective AIDS vaccine is to generate immunity that will prevent human immunodeficien...
Live attenuated measles virus is one of the most efficient and safest vaccines available, making it ...
HIV vaccine mediated efficacy, using an expanded live attenuated recombinant varicella virus-vectore...