AbstractBudding yeast replication origins are activated during S phase according to a predetermined temporal programme. Two recent studies indicate that this programme is executed, at least in part, by the S-phase-promoting cyclins that act to assemble a pre-initiation complex which includes the Cdc45 protein
DNA replication is restricted to a specific time window of the cell cycle, called S phase. Successfu...
Eukaryotic DNA replication relies on a tight two-step regulation to maintain genome stability and en...
SummaryDifferent replication origins in eukaryotes are activated at different times during S phase. ...
AbstractBudding yeast replication origins are activated during S phase according to a predetermined ...
AbstractBackground: DNA replication and mitosis are triggered by activation of kinase complexes, eac...
AbstractRecent results have provided substantial new insights into how the initiation of DNA replica...
In Sacchromyces cerevisiae, it is well known that bidirectional replication initiates at sequence sp...
In order for cells to divide, they must replicate their chromosomes precisely once. This replication...
SummaryBackgroundChromosomal DNA replication in eukaryotes initiates from multiple origins of replic...
AbstractEukaryotic genomes are replicated from large numbers of replication origins distributed on m...
SummaryInitiation of eukaryotic DNA synthesis occurs at origins of replication that are utilized wit...
Activation (in the following referred to as firing) of replication origins is a continuous and irrev...
Similarly to metazoans, the budding yeast Saccharomyces cereviasiae replicates its genome with a def...
DNA replication initiates from defined locations called replication origins; some origins are highly...
AbstractA sophisticated molecular switch ensures that replication origins are activated just once in...
DNA replication is restricted to a specific time window of the cell cycle, called S phase. Successfu...
Eukaryotic DNA replication relies on a tight two-step regulation to maintain genome stability and en...
SummaryDifferent replication origins in eukaryotes are activated at different times during S phase. ...
AbstractBudding yeast replication origins are activated during S phase according to a predetermined ...
AbstractBackground: DNA replication and mitosis are triggered by activation of kinase complexes, eac...
AbstractRecent results have provided substantial new insights into how the initiation of DNA replica...
In Sacchromyces cerevisiae, it is well known that bidirectional replication initiates at sequence sp...
In order for cells to divide, they must replicate their chromosomes precisely once. This replication...
SummaryBackgroundChromosomal DNA replication in eukaryotes initiates from multiple origins of replic...
AbstractEukaryotic genomes are replicated from large numbers of replication origins distributed on m...
SummaryInitiation of eukaryotic DNA synthesis occurs at origins of replication that are utilized wit...
Activation (in the following referred to as firing) of replication origins is a continuous and irrev...
Similarly to metazoans, the budding yeast Saccharomyces cereviasiae replicates its genome with a def...
DNA replication initiates from defined locations called replication origins; some origins are highly...
AbstractA sophisticated molecular switch ensures that replication origins are activated just once in...
DNA replication is restricted to a specific time window of the cell cycle, called S phase. Successfu...
Eukaryotic DNA replication relies on a tight two-step regulation to maintain genome stability and en...
SummaryDifferent replication origins in eukaryotes are activated at different times during S phase. ...
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