Episomal-based generation of an iPS cell line from human fetal foreskin fibroblasts
- Matz, Peggy
- Adjaye, James
Publication date
January 2016
DOI Publisher
The Authors. Published by Elsevier B.V. ISSN
1873-5061 Citation count (estimate)
1Abstract
AbstractHuman fetal foreskin fibroblasts (HFF1) were used to generate the iPSC line epiHFF1-B1 employing a combination of three episomal-based plasmids expressing OCT4, SOX2, NANOG, LIN28, c-MYC, and KLF4. Pluripotency was confirmed both in vivo and in vitro. The transcriptome profile of epiHFF1-B1 and the human embryonic stem cell line—H1 have a pearson correlation of 0.936
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