Albumin to creatinine ratio in a random urine sample: Correlation with severity of preeclampsia

AbstractBackgroundAlbumin to creatinine ratio (ACR) in random urine samples correlates well with 24-h protein excretion in potential glomerulopathy as in diabetic renal microangiopathy. Using this ratio as an appropriate screening test for proteinuria or for the disease severity in hypertensive disorders with pregnancy needs still to be verified.ObjectiveTo investigate the role of albumin to creatinine ratio in a random urine sample for assessment of severity of preeclampsia.Patients & methodsTwo separate groups, fifty women each, were enrolled. All were pregnant at their third trimester with confirmed preeclampsia. Based on their blood pressure levels, Group A, included patients with mild form of preeclampsia, whereas group B included cases with severe form. Albumin to creatinine ratio in random urine samples and the 24-h protein content in urine were assessed.ResultsACR and the 24-h urine protein excretion were significantly correlated, (r=0.583, p