Two-year neurodevelopmental outcomes of infants undergoing neonatal cardiac surgery for interrupted aortic arch: A descriptive analysis

Joynt, Chloe A.
Robertson, Charlene M.T.
Cheung, Po-Yin
Nettel-Aguirre, Alberto
Joffe, Ari R.
Sauve, Reg S.
Biggs, Wayne S.G.
Leonard, Norma J.
Ross, David B.
Rebeyka, Ivan M.

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Publication date

October 2009

DOI

10.1016/j.jtcvs.2009.03.016

Publisher

The American Association for Thoracic Surgery. Published by Mosby, Inc.

ISSN

0022-5223

Citation count (estimate)

Abstract

ObjectiveThis study determined neurodevelopmental outcomes of survivors of neonatal cardiac surgery for interrupted aortic arch through an interprovincial program and explored preoperative, intraoperative, and postoperative outcome predictors.MethodsChildren who underwent neonatal cardiac surgery for interrupted aortic arch at 6 weeks old or younger between 1996 and 2006 had a multidisciplinary neurodevelopmental assessment at 18 to 24 months old (mental and psychomotor developmental indices as mean ± SD and delay [score <70]). Survivor outcomes were compared by univariate and multivariate analyses and compared between children with and without chromosomal abnormality.ResultsOutcomes were available for all 26 survivors (mortality, 3.7%). Me...