ABSTRACTDespite increasing antimicrobial resistance and multiple drug resistance in clinical isolates of both Gram-positive and Gram-negative bacteria, there are few novel antimicrobial agents in development. The few new agents that have been recently licensed have tended to have narrow spectra of activity, focused on Gram-positive pathogens, especially methicillin-resistant Staphylococcus aureus (MRSA). This situation is rightly causing concern among clinicians and public health authorities worldwide. This article reviews available data on three new antibacterials currently in development. The cephalosporin ceftobiprole is active against MRSA, Enterococcus faecalis and penicillin-resistant Streptococcus pneumoniae, but otherwise has a spec...
Background: Infections due to multidrug-resistant (MDR) bacteria are increasing both in hospitals an...
The spread of resistance among Gram-positive and Gram-negative bacteria represents a growing challen...
Multidrug resistance in Gram-positive pathogens emerged as a major therapeutic challenge over two de...
AbstractSince the 1970s, resistance to antimicrobial agents has become an escalating problem. In the...
AbstractMultidrug resistance in Gram-positive pathogens emerged as a major therapeutic challenge ove...
Antimicrobial resistance is a global concern. Over the past few years, considerable efforts and reso...
Antimicrobial resistance is a serious global threat. There is a global menace of antibiotic resistan...
ABSTRACTThere is a clinical need for new treatment options for serious Gram-positive infections. Rec...
ABSTRACTAntibacterial research over the past 50 years has been focused on meeting medical needs caus...
Growing bacterial resistance in Gram-positive pathogens means that what were once effective and inex...
ABSTRACTThe proportion of pathogens causing hospital-onset infections that are resistant to antimicr...
A weak antibiotic pipeline and the increase in drug-resistant pathogens have led to calls for more n...
AbstractMethicillin-resistant Staphylococcus aureus (MRSA), both hospital-acquired and community-acq...
Since 2010 the new antimicrobials introduced have activity against resistant Gram negative bacteria,...
AbstractGrowing bacterial resistance in Gram-positive pathogens means that what were once effective ...
Background: Infections due to multidrug-resistant (MDR) bacteria are increasing both in hospitals an...
The spread of resistance among Gram-positive and Gram-negative bacteria represents a growing challen...
Multidrug resistance in Gram-positive pathogens emerged as a major therapeutic challenge over two de...
AbstractSince the 1970s, resistance to antimicrobial agents has become an escalating problem. In the...
AbstractMultidrug resistance in Gram-positive pathogens emerged as a major therapeutic challenge ove...
Antimicrobial resistance is a global concern. Over the past few years, considerable efforts and reso...
Antimicrobial resistance is a serious global threat. There is a global menace of antibiotic resistan...
ABSTRACTThere is a clinical need for new treatment options for serious Gram-positive infections. Rec...
ABSTRACTAntibacterial research over the past 50 years has been focused on meeting medical needs caus...
Growing bacterial resistance in Gram-positive pathogens means that what were once effective and inex...
ABSTRACTThe proportion of pathogens causing hospital-onset infections that are resistant to antimicr...
A weak antibiotic pipeline and the increase in drug-resistant pathogens have led to calls for more n...
AbstractMethicillin-resistant Staphylococcus aureus (MRSA), both hospital-acquired and community-acq...
Since 2010 the new antimicrobials introduced have activity against resistant Gram negative bacteria,...
AbstractGrowing bacterial resistance in Gram-positive pathogens means that what were once effective ...
Background: Infections due to multidrug-resistant (MDR) bacteria are increasing both in hospitals an...
The spread of resistance among Gram-positive and Gram-negative bacteria represents a growing challen...
Multidrug resistance in Gram-positive pathogens emerged as a major therapeutic challenge over two de...