Membrane traffic: How do GGAs fit in with the adaptors?
- Black, Michael W.
- Pelham, Hugh R.B.
Publication date
June 2001
DOI Publisher
Elsevier Science Ltd. ISSN
0960-9822Abstract
AbstractThe AP-1 adaptor complex has been cast as the major player in clathrin coat formation for vesicular transport from the trans-Golgi to the endocytic pathway. But new results on ‘GGA’ proteins have raised doubts about this paradigm and suggest both a new sorting mechanism and an unexpected complexity in the roles of clathrin
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