BackgroundNeoplastic meningitis (NM) is a devastating neurological complication of cancer that needs to be diagnosed in the early stages of disease. Polymerase chain reaction detection of epithelial growth factor receptor (EGFR) mutations in cerebrospinal fluid (CSF), which are predictive markers for EGFR tyrosine kinase inhibitor therapy in lung cancer, might be important to diagnose and to treat NM in patients with lung cancer. In this study, we attempted to detect EGFR mutations in CSF and to compare EGFR status between CSF and primary or metastatic lesions in patients with lung adenocarcinoma suspected of NM.MethodsTwenty-nine patients with lung adenocarcinoma suspected of having NM underwent lumbar puncture. EGFR status of CSF was anal...
Epidermal growth factor receptor (EGFR) mutation testing in advanced non-small-cell lung cancer (NSC...
Introduction:The epidermal growth factor receptor (EGFR) gene status including tyrosine kinase domai...
Background: Somatic mutations of the epidermal growth factor receptor (EGFR) are reportedly associat...
BackgroundNeoplastic meningitis (NM) is a devastating neurological complication of cancer that needs...
Background: EGFR tyrosine kinase inhibitors (TKIs) have revolutionized the therapeutic approach for ...
IntroductionThe majority of patients with non-small cell lung cancer (NSCLC) develop distant metasta...
Introduction:To evaluate epidermal growth factor receptor (EGFR) mutation status in lung adenocarcin...
Background:This study aimed to explore the potential association of mutation in the epidermal growth...
Background: The prevalence of epidermal growth factor receptor (EGFR) mutations in non-small cell lu...
BackgroundLeptomeningeal carcinomatosis (LC) is a detrimental complication of patients with non–smal...
Background: Leptomeningeal carcinomatosis (LC) is a detrimental complication of patients with non-sm...
Introduction: Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor therapy is effective...
Purpose: To investigate the epidermal growth factor receptor (EGFR) gene mutations and analyze their...
Background:Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) p...
Background: We aim to evaluate the influence of the timing of leptomeningeal metastasis (LM) occurre...
Epidermal growth factor receptor (EGFR) mutation testing in advanced non-small-cell lung cancer (NSC...
Introduction:The epidermal growth factor receptor (EGFR) gene status including tyrosine kinase domai...
Background: Somatic mutations of the epidermal growth factor receptor (EGFR) are reportedly associat...
BackgroundNeoplastic meningitis (NM) is a devastating neurological complication of cancer that needs...
Background: EGFR tyrosine kinase inhibitors (TKIs) have revolutionized the therapeutic approach for ...
IntroductionThe majority of patients with non-small cell lung cancer (NSCLC) develop distant metasta...
Introduction:To evaluate epidermal growth factor receptor (EGFR) mutation status in lung adenocarcin...
Background:This study aimed to explore the potential association of mutation in the epidermal growth...
Background: The prevalence of epidermal growth factor receptor (EGFR) mutations in non-small cell lu...
BackgroundLeptomeningeal carcinomatosis (LC) is a detrimental complication of patients with non–smal...
Background: Leptomeningeal carcinomatosis (LC) is a detrimental complication of patients with non-sm...
Introduction: Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor therapy is effective...
Purpose: To investigate the epidermal growth factor receptor (EGFR) gene mutations and analyze their...
Background:Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) p...
Background: We aim to evaluate the influence of the timing of leptomeningeal metastasis (LM) occurre...
Epidermal growth factor receptor (EGFR) mutation testing in advanced non-small-cell lung cancer (NSC...
Introduction:The epidermal growth factor receptor (EGFR) gene status including tyrosine kinase domai...
Background: Somatic mutations of the epidermal growth factor receptor (EGFR) are reportedly associat...