AbstractTwo integral membrane proteins, Patched and Smoothened, were for a long time thought to comprise a preformed receptor complex for secreted Hedgehog signalling proteins. Recent analyses of the subcellular distribution of these proteins argue strongly against this simple model
honors thesisCollege of ScienceChemistryThe Hedgehog (Hh) pathway is a cell signaling pathway that i...
International audienceThe Hedgehog (Hh) signalling cascade is highly conserved and involved in devel...
The Hedgehog (Hh)-signalling pathway is a crucial, evolutionarily conserved signalling cascade impor...
AbstractSecreted signaling proteins of the Hedgehog family organize spatial pattern during animal de...
AbstractSecreted proteins of the Hedgehog (Hh) family have diverse organizing roles in animal develo...
AbstractThe tumor suppressor gene patched (ptc) encodes an approximately 140 kDa polytopic transmemb...
SummaryHedgehog (HH) is a major secreted morphogen involved in development, stem cell maintenance an...
AbstractTwo integral membrane proteins, Patched and Smoothened, were for a long time thought to comp...
The Hedgehog (Hh) signaling pathway plays an evolutionarily conserved role in patterning fields of c...
A recent paper in Cell (Yao et al., 2006) and two papers in Developmental Cell (Tenzen et al., 2006;...
AbstractThe Hedgehog (Hh) signal is transmitted by two receptor molecules, Patched (Ptc) and Smoothe...
SummaryAn intracellular conformational switch in the serpentine transmembrane protein Smoothened app...
AbstractBy coupling to cholesterol, Hedgehog can be anchored to the cells where it is made, yet to a...
AbstractArrestins are best known for terminating signaling by G protein coupled receptors. New bindi...
Hedgehog (Hh) signaling is critical for many developmental events and must be restrained to prevent ...
honors thesisCollege of ScienceChemistryThe Hedgehog (Hh) pathway is a cell signaling pathway that i...
International audienceThe Hedgehog (Hh) signalling cascade is highly conserved and involved in devel...
The Hedgehog (Hh)-signalling pathway is a crucial, evolutionarily conserved signalling cascade impor...
AbstractSecreted signaling proteins of the Hedgehog family organize spatial pattern during animal de...
AbstractSecreted proteins of the Hedgehog (Hh) family have diverse organizing roles in animal develo...
AbstractThe tumor suppressor gene patched (ptc) encodes an approximately 140 kDa polytopic transmemb...
SummaryHedgehog (HH) is a major secreted morphogen involved in development, stem cell maintenance an...
AbstractTwo integral membrane proteins, Patched and Smoothened, were for a long time thought to comp...
The Hedgehog (Hh) signaling pathway plays an evolutionarily conserved role in patterning fields of c...
A recent paper in Cell (Yao et al., 2006) and two papers in Developmental Cell (Tenzen et al., 2006;...
AbstractThe Hedgehog (Hh) signal is transmitted by two receptor molecules, Patched (Ptc) and Smoothe...
SummaryAn intracellular conformational switch in the serpentine transmembrane protein Smoothened app...
AbstractBy coupling to cholesterol, Hedgehog can be anchored to the cells where it is made, yet to a...
AbstractArrestins are best known for terminating signaling by G protein coupled receptors. New bindi...
Hedgehog (Hh) signaling is critical for many developmental events and must be restrained to prevent ...
honors thesisCollege of ScienceChemistryThe Hedgehog (Hh) pathway is a cell signaling pathway that i...
International audienceThe Hedgehog (Hh) signalling cascade is highly conserved and involved in devel...
The Hedgehog (Hh)-signalling pathway is a crucial, evolutionarily conserved signalling cascade impor...
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