Predictors of advanced disease and late presentation in new HIV diagnoses reported to the surveillance system in Spain

Oliva, Jesús
Díez, Mercedes
Galindo, Silvia
Cevallos, Carlos
Izquierdo, Ana
Cereijo, Javier
Arrillaga, Arantxa
Nicolau, Antonio
Fernández, Ana
Álvarez, Mara
Castilla, Jesús
Martínez, Eva
López, Irene
Vivés, Nuria

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Publication date

April 2014

DOI

10.1016/j.gaceta.2013.06.009

Publisher

SESPAS. Published by Elsevier España, S.L.

ISSN

0213-9111

Citation count (estimate)

Abstract

AbstractObjectiveTo present surveillance data on advanced disease (AD) and late presentation (LP) of HIV in Spain and their determinants.MethodsWe included all new HIV diagnoses notified by the autonomous regions that consistently reported such cases throughout the period 2007–2011. Coverage was 54% of the total Spanish population. Data sources consisted of clinicians, laboratories and medical records. AD was defined as the presence of a CD4 cell count <200cells/μL in the first test after HIV diagnosis, while LP was defined as the presence of a CD4 cell count <350cells/μL after HIV diagnosis. Odds ratios and their 95% confidence intervals (OR, 95% CI) were used as the measure of association. Logistic regressions were fit to identify predict...