ABSTRACTThe identification of novel helper T (Th) cell subsets, i.e., IL-17-producing Th cells (Th17 cells) and regulatory T cells (Treg cells), provided new insight into our understanding of the molecular mechanisms involved in the development of infectious and autoimmune diseases as well as immune responses, and thus led to revision of the classic Th1/Th2 paradigm. Several current lines of evidence from gene-deficient mice indicate that IL-17 and Th17 cells, but not IFN-y and Th1 cells, are responsible for the development of autoimmune diseases such as murine arthritis and encephalomyelitis, which have classically been considered to be Th1-mediated disorders. Th17 cells may also contribute to the pathogenesis of classically recognized Th2...
Atopic dermatitis (AD) is generally regarded as a type 2 helper T (Th2)-mediated inflammatory skin d...
The view of CD4 T-cell-mediated immunity as a balance between distinct lineages of Th1 and Th2 cells...
Adaptive immunity is controlled by CD4+ T cells that develop into functionally distinct T helper (Th...
IL-17-producing CD4+ T cells (Th17 cells) are understood to be a distinct lineage of CD4+ T helper (...
T helper 17 (Th17) cells belong to a recently identified T helper subset, in addition to the traditi...
For more than two decades, immunologists have been using the so-called Th1/Th2 paradigm to explain m...
A new subtype of CD4+ T lymphocytes characterized by the production of interleukin 17, i.e., TH17 ce...
Th17 cells are critical for the clearance of extracellular bacteria and fungi, but also contribute t...
Our understanding of the role of T cells in human disease is undergoing revision as a result of the ...
Recently the Th1/Th2 concept has been revised and Th17 cells have been implicated in allergy. Despit...
With all the incredible progress in scientific research over the past two decades, the trigger of th...
Selective activation of T helper (Th) cell subsets plays an important role in immune response to pat...
The Author(s) 2015. This article is published with open access at Springerlink.com Abstract The end ...
Regulatory T (Treg) cells are considered to inhibit the development of both type 1 (Th1) and type 2 ...
T helper 17 (Th17) cells are characterized by the secretion of IL-17, a proinflammatory cytokine. Th...
Atopic dermatitis (AD) is generally regarded as a type 2 helper T (Th2)-mediated inflammatory skin d...
The view of CD4 T-cell-mediated immunity as a balance between distinct lineages of Th1 and Th2 cells...
Adaptive immunity is controlled by CD4+ T cells that develop into functionally distinct T helper (Th...
IL-17-producing CD4+ T cells (Th17 cells) are understood to be a distinct lineage of CD4+ T helper (...
T helper 17 (Th17) cells belong to a recently identified T helper subset, in addition to the traditi...
For more than two decades, immunologists have been using the so-called Th1/Th2 paradigm to explain m...
A new subtype of CD4+ T lymphocytes characterized by the production of interleukin 17, i.e., TH17 ce...
Th17 cells are critical for the clearance of extracellular bacteria and fungi, but also contribute t...
Our understanding of the role of T cells in human disease is undergoing revision as a result of the ...
Recently the Th1/Th2 concept has been revised and Th17 cells have been implicated in allergy. Despit...
With all the incredible progress in scientific research over the past two decades, the trigger of th...
Selective activation of T helper (Th) cell subsets plays an important role in immune response to pat...
The Author(s) 2015. This article is published with open access at Springerlink.com Abstract The end ...
Regulatory T (Treg) cells are considered to inhibit the development of both type 1 (Th1) and type 2 ...
T helper 17 (Th17) cells are characterized by the secretion of IL-17, a proinflammatory cytokine. Th...
Atopic dermatitis (AD) is generally regarded as a type 2 helper T (Th2)-mediated inflammatory skin d...
The view of CD4 T-cell-mediated immunity as a balance between distinct lineages of Th1 and Th2 cells...
Adaptive immunity is controlled by CD4+ T cells that develop into functionally distinct T helper (Th...