Proteoglycans are complex macromolecules with the potential for extraordinary diversity. Several recent studies have demonstrated important roles for heparan sulfate and chondroitin sulfate proteoglycans (HSPGs and CSPGs) in axon pathfinding and have linked HSPGs to specific signaling pathways. More speculatively, there are hints of a “sugar code,” in which specific sugar modifications might act instructively in guidance decisions. This raises the intriguing possibility that the complexity of neuronal wiring may in part reflect the complexity of proteoglycan modifications
Heparan sulfate proteoglycans (HSPGs) are proteins with long covalently attached sugar side chains o...
Neuronal axons and their growth cones recognize molecular guidance cues within the local environment...
The correct migration and axon extension of neurons in the developing nervous system is essential fo...
Proteoglycans are complex macromolecules with the potential for extraordinary diversity. Several rec...
Proteoglycans are complex macromolecules with the potential for extraordinary diversity. Several rec...
SummaryHeparan sulfates (HSs) are extraordinarily complex extracellular sugar molecules that are cri...
Item does not contain fulltextHeparan sulfates (HSs) are extraordinarily complex extracellular sugar...
SummaryHeparan sulfates (HSs) are extraordinarily complex extracellular sugar molecules that are cri...
Heparan sulfates (HSs) are extraordinarily complex extracellular sugar molecules that are critical c...
AbstractHeparan sulfate proteoglycans (HSPG) are components of the extracellular matrix through whic...
Glycosaminoglycans are sulfated in complex and changing patterns that affect neural development. The...
Heparan sulfate proteoglycans (HSPGs) are proteins with long covalently attached sugar side chains o...
AbstractThe presentation of secreted axon guidance factors plays a major role in shaping central ner...
Heparan sulfate proteoglycans (HSPGs) are proteins with long covalently attached sugar side chains o...
AbstractHeparan sulfate proteoglycans (HSPG) are components of the extracellular matrix through whic...
Heparan sulfate proteoglycans (HSPGs) are proteins with long covalently attached sugar side chains o...
Neuronal axons and their growth cones recognize molecular guidance cues within the local environment...
The correct migration and axon extension of neurons in the developing nervous system is essential fo...
Proteoglycans are complex macromolecules with the potential for extraordinary diversity. Several rec...
Proteoglycans are complex macromolecules with the potential for extraordinary diversity. Several rec...
SummaryHeparan sulfates (HSs) are extraordinarily complex extracellular sugar molecules that are cri...
Item does not contain fulltextHeparan sulfates (HSs) are extraordinarily complex extracellular sugar...
SummaryHeparan sulfates (HSs) are extraordinarily complex extracellular sugar molecules that are cri...
Heparan sulfates (HSs) are extraordinarily complex extracellular sugar molecules that are critical c...
AbstractHeparan sulfate proteoglycans (HSPG) are components of the extracellular matrix through whic...
Glycosaminoglycans are sulfated in complex and changing patterns that affect neural development. The...
Heparan sulfate proteoglycans (HSPGs) are proteins with long covalently attached sugar side chains o...
AbstractThe presentation of secreted axon guidance factors plays a major role in shaping central ner...
Heparan sulfate proteoglycans (HSPGs) are proteins with long covalently attached sugar side chains o...
AbstractHeparan sulfate proteoglycans (HSPG) are components of the extracellular matrix through whic...
Heparan sulfate proteoglycans (HSPGs) are proteins with long covalently attached sugar side chains o...
Neuronal axons and their growth cones recognize molecular guidance cues within the local environment...
The correct migration and axon extension of neurons in the developing nervous system is essential fo...