AbstractSoluble factors, NSF and SNAPs, are required at many membrane fusion events within the cell. They interact with a class of type II integral membrane proteins termed SNAP receptors, or SNAREs. Interaction between cognate SNAREs on opposing membranes is a prerequisite for NSF dependent membrane fusion. NSF is an ATPase which will disrupt complexes composed of different SNAREs. However, there is increasingly abundant evidence that the SNARE complex recognised by NSF does not bridge the two fusing membranes, but rather is composed of SNAREs in the same membrane. The essential role of NSF may be to prime SNAREs for a direct role during fusion. The best characterised SNAREs in the Golgi are Sed5p in yeast and its mammalian homologue synta...
AbstractEukaryotic cells distribute materials among intracellular organelles and secrete into the ex...
AbstractTwo distinct sets of soluble N-ethylmaleimide-sensitive factor attachment protein receptors ...
AbstractN-Ethylmaleimide-sensitive factor (NSF) plays a key role in vesicular traffic by disassembli...
AbstractSoluble factors, NSF and SNAPs, are required at many membrane fusion events within the cell....
The transport of proteins between various compartments of the secretory pathway occurs by the buddin...
Fusion of transport vesicles with their target organelles involves specific membrane proteins, SNARE...
Soluble NSF attachment protein receptor (SNARE) proteins are essential for membrane fusion in transp...
AbstractSNAREs are small coiled-coil proteins required for specific membrane fusion events in eukary...
AbstractIntracellular vesicular transport involves targeting of vesicles to their correct destinatio...
AbstractOperation of the secretory pathway in eukaryotic cells requires the selective docking and fu...
AbstractIntracellular membrane fusion is conserved from yeast to man as well as among different intr...
AbstractThe fusion of endoplasmic reticulum (ER) membranes in yeast does not require Sec18p/NSF and ...
AbstractSNARE proteins are sufficient to fuse artificial membranes together. In the cell, vesicle tr...
AbstractSNAREs and Rab GTPases cooperate in vesicle transport through a mechanism yet poorly underst...
AbstractRecent studies show that NSF, isolated over 15 years ago as a protein required for membrane ...
AbstractEukaryotic cells distribute materials among intracellular organelles and secrete into the ex...
AbstractTwo distinct sets of soluble N-ethylmaleimide-sensitive factor attachment protein receptors ...
AbstractN-Ethylmaleimide-sensitive factor (NSF) plays a key role in vesicular traffic by disassembli...
AbstractSoluble factors, NSF and SNAPs, are required at many membrane fusion events within the cell....
The transport of proteins between various compartments of the secretory pathway occurs by the buddin...
Fusion of transport vesicles with their target organelles involves specific membrane proteins, SNARE...
Soluble NSF attachment protein receptor (SNARE) proteins are essential for membrane fusion in transp...
AbstractSNAREs are small coiled-coil proteins required for specific membrane fusion events in eukary...
AbstractIntracellular vesicular transport involves targeting of vesicles to their correct destinatio...
AbstractOperation of the secretory pathway in eukaryotic cells requires the selective docking and fu...
AbstractIntracellular membrane fusion is conserved from yeast to man as well as among different intr...
AbstractThe fusion of endoplasmic reticulum (ER) membranes in yeast does not require Sec18p/NSF and ...
AbstractSNARE proteins are sufficient to fuse artificial membranes together. In the cell, vesicle tr...
AbstractSNAREs and Rab GTPases cooperate in vesicle transport through a mechanism yet poorly underst...
AbstractRecent studies show that NSF, isolated over 15 years ago as a protein required for membrane ...
AbstractEukaryotic cells distribute materials among intracellular organelles and secrete into the ex...
AbstractTwo distinct sets of soluble N-ethylmaleimide-sensitive factor attachment protein receptors ...
AbstractN-Ethylmaleimide-sensitive factor (NSF) plays a key role in vesicular traffic by disassembli...