AbstractATP-binding cassette (ABC) transporters have often been refractory to over-expression. Using the C41(DE3) E. coli as a host strain, membrane vesicles highly enriched (>50%) in YvcC, a previously uncharacterized ABC transporter from Bacillus subtilis homologous to P-glycoprotein multidrug transporters, were obtained. The functionality of YvcC was assessed by its high vanadate-sensitive ATPase activity and its ability to transport a fluorescent drug, the Hoechst 33342
Membrane proteins are of fundamental importance for all living organisms. They represent up to 30% o...
We would like to thank Herminia de Lencastre (ITQB-AX NOVA), Adriano Henriques (ITQB-AX NOVA) and Pa...
Transport across biological membranes is fundamental for cell survival and is mainly accomplished by...
AbstractATP-binding cassette (ABC) transporters have often been refractory to over-expression. Using...
AbstractABC (ATP-binding cassette) transporters form the largest family of membrane proteins in micr...
The multidrug resistance (MDR) phenotype of cancer cells is mostly associated with overexpression of...
L'émergence du phénotype MDR ( multidrug resistance ) des cellules cancéreuses est souvent corrélée ...
L'analyse du génome de Bacillus subtilis a montré que le gène yvcc code un transporteur ABC ("ATP Bi...
AbstractATP-binding cassette (ABC) transporters are integral membrane proteins that actively transpo...
strains lacking the principal secondary transporter AcrB (Acriflavine resistance protein), as well a...
Bacterial membrane proteins of the SbmA/BacA family are multi-solute transporters that mediate the u...
AbstractYor1p, a Saccharomyces cerevisiae plasma membrane ABC-transporter, is associated to oligomyc...
Multidrug transporters are important and interesting molecular machines that extrude a wide variety ...
The genes encoding ATP-binding cassette (ABC) transporters occupy 2.5% of the genome of Mycobacteriu...
7-13ATP-binding cassette (ABC) transporters utilize the energy present in cellular ATP to drive the...
Membrane proteins are of fundamental importance for all living organisms. They represent up to 30% o...
We would like to thank Herminia de Lencastre (ITQB-AX NOVA), Adriano Henriques (ITQB-AX NOVA) and Pa...
Transport across biological membranes is fundamental for cell survival and is mainly accomplished by...
AbstractATP-binding cassette (ABC) transporters have often been refractory to over-expression. Using...
AbstractABC (ATP-binding cassette) transporters form the largest family of membrane proteins in micr...
The multidrug resistance (MDR) phenotype of cancer cells is mostly associated with overexpression of...
L'émergence du phénotype MDR ( multidrug resistance ) des cellules cancéreuses est souvent corrélée ...
L'analyse du génome de Bacillus subtilis a montré que le gène yvcc code un transporteur ABC ("ATP Bi...
AbstractATP-binding cassette (ABC) transporters are integral membrane proteins that actively transpo...
strains lacking the principal secondary transporter AcrB (Acriflavine resistance protein), as well a...
Bacterial membrane proteins of the SbmA/BacA family are multi-solute transporters that mediate the u...
AbstractYor1p, a Saccharomyces cerevisiae plasma membrane ABC-transporter, is associated to oligomyc...
Multidrug transporters are important and interesting molecular machines that extrude a wide variety ...
The genes encoding ATP-binding cassette (ABC) transporters occupy 2.5% of the genome of Mycobacteriu...
7-13ATP-binding cassette (ABC) transporters utilize the energy present in cellular ATP to drive the...
Membrane proteins are of fundamental importance for all living organisms. They represent up to 30% o...
We would like to thank Herminia de Lencastre (ITQB-AX NOVA), Adriano Henriques (ITQB-AX NOVA) and Pa...
Transport across biological membranes is fundamental for cell survival and is mainly accomplished by...