Sexually transmitted viral infections have the potential to be prevented and treated by topical viricides. Here, Wu et al. (2009) demonstrate that cholesterol-conjugated small interfering RNAs (siRNAs) targeting a cellular receptor combined with an antiviral siRNA when topically applied to mucosal tissue blocked lethal herpes virus infections in mice
There is an urgent need to develop a less aggressive and more effective treatment against cervical l...
AbstractSARS-associated coronavirus was identified as the etiological agent of severe acute respirat...
RNA interference (RNAi) is an emerging and promising therapy for a wide range of respiratory viral i...
<div><p>(A) Intravaginal application of siRNAs mixed with a transfection lipid inhibits sexual trans...
Herpes simplex virus 2 (HSV-2) infection causes significant morbidity and is an important cofactor f...
The global impact of sexually transmitted infections (STIs) is significant. The sexual transmission ...
RNA interference (RNAi), which is mediated by small interfering RNAs (siRNAs) derived from viral gen...
RNA interference (RNAi) is a process by which introduced small interfering RNA (siRNA) can cause the...
Acute viral respiratory tract infections (AVRIs) are a major burden on human health and global econo...
AbstractSmall interfering RNA (siRNA) is currently being evaluated not only as a powerful tool for f...
Background: Equine herpesvirus type 1 (EHV-1), a member of the Alphaherpesvirinae, is spread via nas...
AbstractThe aim of this study was to evaluate the use of RNA interference to inhibit herpes simplex ...
<div><p>Herpes simplex virus type 1 (HSV-1), a member of the <i>herpesviridae</i>, causes a variety ...
Cholesterol 25-hydroxylase (CH25H) is an interferon (IFN)-stimulated gene that shows broad antiviral...
Herpes simplex virus type 1 (HSV‐1) is a human pathogen that causes recurrent infections. Acyclovir‐...
There is an urgent need to develop a less aggressive and more effective treatment against cervical l...
AbstractSARS-associated coronavirus was identified as the etiological agent of severe acute respirat...
RNA interference (RNAi) is an emerging and promising therapy for a wide range of respiratory viral i...
<div><p>(A) Intravaginal application of siRNAs mixed with a transfection lipid inhibits sexual trans...
Herpes simplex virus 2 (HSV-2) infection causes significant morbidity and is an important cofactor f...
The global impact of sexually transmitted infections (STIs) is significant. The sexual transmission ...
RNA interference (RNAi), which is mediated by small interfering RNAs (siRNAs) derived from viral gen...
RNA interference (RNAi) is a process by which introduced small interfering RNA (siRNA) can cause the...
Acute viral respiratory tract infections (AVRIs) are a major burden on human health and global econo...
AbstractSmall interfering RNA (siRNA) is currently being evaluated not only as a powerful tool for f...
Background: Equine herpesvirus type 1 (EHV-1), a member of the Alphaherpesvirinae, is spread via nas...
AbstractThe aim of this study was to evaluate the use of RNA interference to inhibit herpes simplex ...
<div><p>Herpes simplex virus type 1 (HSV-1), a member of the <i>herpesviridae</i>, causes a variety ...
Cholesterol 25-hydroxylase (CH25H) is an interferon (IFN)-stimulated gene that shows broad antiviral...
Herpes simplex virus type 1 (HSV‐1) is a human pathogen that causes recurrent infections. Acyclovir‐...
There is an urgent need to develop a less aggressive and more effective treatment against cervical l...
AbstractSARS-associated coronavirus was identified as the etiological agent of severe acute respirat...
RNA interference (RNAi) is an emerging and promising therapy for a wide range of respiratory viral i...