The catabolite gene activation system ofE.coli may be directly involved in regulation of bacteriophage λ development

AbstractThe primary structure of bacteriophage λ DNA has been searched for the presence of consensus CAP binding sites. Four putative CAP binding sites have been found on the λ genome, indicating that the catabolite gene activation system of E.coli may be directly involved in the regulation of λ development. Molecular mechanisms of putative cAMP-CAP-mediated stimulation of lysogenic and lytic responses are discussed