AbstractThe membrane leakage caused by the cell penetrating peptide Tp10, a variant of transportan, was studied in large unilamellar vesicles with the entrapped fluorophore calcein. The vesicles were composed of zwitterionic 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine. A significant decrease in membrane leakage was found when the 55kDa streptavidin protein was attached to Tp10. When a 5.4kDa peptide nucleic acid molecule was attached, the membrane leakage was comparable to that caused by Tp10 alone. The results suggest that direct membrane effects may cause membrane translocation of Tp10 alone and of smaller complexes, whereas these effects do not contribute for larger cargoes
Cell-penetrating peptides (CPPs) have been extensively studied during the past decade, because of th...
International audienceThe ability of cell penetrating peptides (CPPs) to cross cell membranes has fo...
AbstractPeptides derived from the unprocessed N-termini of mouse and bovine prion proteins (mPrPp an...
AbstractThe mechanism of the interaction between the cell-penetrating peptide transportan 10 (tp10) ...
Transportan 10 (TP10) is a 21 residues peptide that belongs to the family of the antimicrobial and c...
AbstractCell-penetrating peptides with the ability to escape endosomes and reach the target are of g...
AbstractThe PepFect family of cell‐penetrating peptides (CPPs) was designed to improve the delivery ...
Continuous progress has been made in the development of new molecules for therapeutic purposes. This...
Cell penetrating peptides (CPPs) have been successfully used to mediate the intracellular delivery o...
Although cell-penetrating peptides (CPPs), also denoted protein transduction domains (PTDs), have be...
The cell membrane is an impermeable barrier for most macromolecules. Recently discovered cell-penetr...
Structure analysis of the cell-penetrating peptide transportan 10 (TP10) revealed an exemplary range...
La nécessité de délivrer des médicaments directement dans les cellules est grandissante avec le déve...
AbstractUsing a high throughput screen, we have identified a family of 12-residue long peptides that...
AbstractCell-penetrating peptides (CPPs) are able to translocate across biological membranes and del...
Cell-penetrating peptides (CPPs) have been extensively studied during the past decade, because of th...
International audienceThe ability of cell penetrating peptides (CPPs) to cross cell membranes has fo...
AbstractPeptides derived from the unprocessed N-termini of mouse and bovine prion proteins (mPrPp an...
AbstractThe mechanism of the interaction between the cell-penetrating peptide transportan 10 (tp10) ...
Transportan 10 (TP10) is a 21 residues peptide that belongs to the family of the antimicrobial and c...
AbstractCell-penetrating peptides with the ability to escape endosomes and reach the target are of g...
AbstractThe PepFect family of cell‐penetrating peptides (CPPs) was designed to improve the delivery ...
Continuous progress has been made in the development of new molecules for therapeutic purposes. This...
Cell penetrating peptides (CPPs) have been successfully used to mediate the intracellular delivery o...
Although cell-penetrating peptides (CPPs), also denoted protein transduction domains (PTDs), have be...
The cell membrane is an impermeable barrier for most macromolecules. Recently discovered cell-penetr...
Structure analysis of the cell-penetrating peptide transportan 10 (TP10) revealed an exemplary range...
La nécessité de délivrer des médicaments directement dans les cellules est grandissante avec le déve...
AbstractUsing a high throughput screen, we have identified a family of 12-residue long peptides that...
AbstractCell-penetrating peptides (CPPs) are able to translocate across biological membranes and del...
Cell-penetrating peptides (CPPs) have been extensively studied during the past decade, because of th...
International audienceThe ability of cell penetrating peptides (CPPs) to cross cell membranes has fo...
AbstractPeptides derived from the unprocessed N-termini of mouse and bovine prion proteins (mPrPp an...