In this issue of Immunity, Teng et al. (2008) and Dorsett et al. (2008) report that activation-induced cytidine deaminase in B cells is repressed by microRNA-155. Relief of repression is associated with defective affinity maturation and increased Myc-Igh translocations
Although the immune response is predominantly controlled at the transcriptional level, microRNA-medi...
SummaryB lymphocytes perform somatic hypermutation and class-switch recombination (CSR) of the immun...
SummaryMicroRNA (miRNA)-dependent regulation of gene expression confers robustness to cellular pheno...
In this issue of Immunity, Teng et al. (2008) and Dorsett et al. (2008) report that activation-induc...
SummaryMicroRNAs (miRNAs) are small noncoding RNAs that regulate vast networks of genes that share m...
Small regulatory RNAs supplement the canonical pathways of gene regulation through diverse mechanism...
International audienceMicroRNAs (miRNAs) are small noncoding RNAs that regulate vast networks of gen...
MicroRNAs (miRNAs) are found in most metazoan organisms as well as in viruses and are implicated in ...
MicroRNA (miRNA) control has emerged as a critical regulatory principle in the mammalian immune syst...
Vigorito et al. (2007) report (in this issue of Immunity) that B cells require microRNA (miR)-155 fo...
The molecular mechanisms that underlie T cell anergy remain unclear. In this issue of Immunity, Teag...
SummarymicroRNA-155 (miR-155) is expressed by cells of the immune system after activation and has be...
The importance of individual target genes for miRNA activity has been difficult to establish. In thi...
MicroRNAs (miRNAs) are key players in gene regulation that target specific mRNAs for degradation or ...
<p>Immunity is broadly defined as a mechanism of protection against non-self entities, a process whi...
Although the immune response is predominantly controlled at the transcriptional level, microRNA-medi...
SummaryB lymphocytes perform somatic hypermutation and class-switch recombination (CSR) of the immun...
SummaryMicroRNA (miRNA)-dependent regulation of gene expression confers robustness to cellular pheno...
In this issue of Immunity, Teng et al. (2008) and Dorsett et al. (2008) report that activation-induc...
SummaryMicroRNAs (miRNAs) are small noncoding RNAs that regulate vast networks of genes that share m...
Small regulatory RNAs supplement the canonical pathways of gene regulation through diverse mechanism...
International audienceMicroRNAs (miRNAs) are small noncoding RNAs that regulate vast networks of gen...
MicroRNAs (miRNAs) are found in most metazoan organisms as well as in viruses and are implicated in ...
MicroRNA (miRNA) control has emerged as a critical regulatory principle in the mammalian immune syst...
Vigorito et al. (2007) report (in this issue of Immunity) that B cells require microRNA (miR)-155 fo...
The molecular mechanisms that underlie T cell anergy remain unclear. In this issue of Immunity, Teag...
SummarymicroRNA-155 (miR-155) is expressed by cells of the immune system after activation and has be...
The importance of individual target genes for miRNA activity has been difficult to establish. In thi...
MicroRNAs (miRNAs) are key players in gene regulation that target specific mRNAs for degradation or ...
<p>Immunity is broadly defined as a mechanism of protection against non-self entities, a process whi...
Although the immune response is predominantly controlled at the transcriptional level, microRNA-medi...
SummaryB lymphocytes perform somatic hypermutation and class-switch recombination (CSR) of the immun...
SummaryMicroRNA (miRNA)-dependent regulation of gene expression confers robustness to cellular pheno...
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