As the home for the bulk of eukaryotic genomes, the nucleus is a perfect venue for observing intricate regulatory mechanisms involving interactions between DNA, RNA, and protein. These interactions have evolved beyond the original central dogma concept, and the papers featured in this Select highlight some recent and exciting examples of these mechanisms
Development of complex multicellular organisms depends on precise spatiotemporal regulation of trans...
Localization of genes to different parts of the nucleus has the potential to promote activation or s...
A report on the Keystone Symposium 'Epigenetics: Regulation of Chromatin Structure in Development an...
As the home for the bulk of eukaryotic genomes, the nucleus is a perfect venue for observing intrica...
SummaryAlthough eukaryotic nuclei contain distinct architectural structures associated with noncodin...
Polycomb group (PcG) proteins function as chromatin-based transcriptional repressors that are essen...
Precise spatio-temporal regulation of gene expression is required for development of multicellular o...
Over 200 cell types exist within the human body, each being different in morphology and function, ye...
RNA interference (RNAi) pathways can result in sequence-specific transcriptional gene silencing on t...
The nuclear organization of chromosomes has been suggested to be associated with regulation of gene ...
AbstractEukaryotic cells store their genome inside a nucleus, a dedicated organelle shielded by a do...
Transcription is regulated on different levels to ensure that genes are expressed at the correct tim...
SummaryMultiple mechanisms have evolved to regulate the eukaryotic genome. We have identified CTN-RN...
Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate. The Po...
CpG islands (CGIs) are associated with most mammalian gene promoters. A subset of CGIs act as polyco...
Development of complex multicellular organisms depends on precise spatiotemporal regulation of trans...
Localization of genes to different parts of the nucleus has the potential to promote activation or s...
A report on the Keystone Symposium 'Epigenetics: Regulation of Chromatin Structure in Development an...
As the home for the bulk of eukaryotic genomes, the nucleus is a perfect venue for observing intrica...
SummaryAlthough eukaryotic nuclei contain distinct architectural structures associated with noncodin...
Polycomb group (PcG) proteins function as chromatin-based transcriptional repressors that are essen...
Precise spatio-temporal regulation of gene expression is required for development of multicellular o...
Over 200 cell types exist within the human body, each being different in morphology and function, ye...
RNA interference (RNAi) pathways can result in sequence-specific transcriptional gene silencing on t...
The nuclear organization of chromosomes has been suggested to be associated with regulation of gene ...
AbstractEukaryotic cells store their genome inside a nucleus, a dedicated organelle shielded by a do...
Transcription is regulated on different levels to ensure that genes are expressed at the correct tim...
SummaryMultiple mechanisms have evolved to regulate the eukaryotic genome. We have identified CTN-RN...
Polycomb group (PcG) proteins play critical roles in the epigenetic inheritance of cell fate. The Po...
CpG islands (CGIs) are associated with most mammalian gene promoters. A subset of CGIs act as polyco...
Development of complex multicellular organisms depends on precise spatiotemporal regulation of trans...
Localization of genes to different parts of the nucleus has the potential to promote activation or s...
A report on the Keystone Symposium 'Epigenetics: Regulation of Chromatin Structure in Development an...