AbstractBackgroundTumor necrosis factor is an important mediator of lung transplant acute rejection. Soluble type I tumor necrosis factor receptor binds to tumor necrosis factor-α and -β and inhibits their function. The objectives of this study were to demonstrate efficient in vivo gene transfer of a soluble type I tumor necrosis factor receptor fusion protein (sTNF-RI-Ig) and determine its effects on lung allograft acute rejection.MethodsThree groups of Fischer rats (n = 6 per group) underwent recipient intramuscular transfection 24 hours before transplantation with saline, 1 × 1010 plaque-forming units of control adenovirus encoding β-galactosidase, or 1 × 1010 plaque-forming units of adenovirus encoding human sTNF-RI-Ig (Ad.sTNF-RI-Ig). ...
AbstractObjective: Proximal pulmonary artery segment transfection may provide beneficial downstream ...
AbstractObjective: Nitric oxide regulates vascular tone, inhibits platelet aggregation, and inhibits...
Objective: Electroporation mediated transfer of plasmid DNA into peripheral muscle results in high t...
AbstractBackgroundTumor necrosis factor is an important mediator of lung transplant acute rejection....
AbstractObjectiveTumor necrosis factor is an important mediator of lung transplant ischemia-reperfus...
AbstractBackground: The aim of the current work was to study the feasibility of functional gene tran...
ObjectiveMultiple gene transfer might permit modulation of concurrent biochemical pathways involved ...
none7Objective: Multiple gene transfer might permit modulation of concurrent biochemical pathways in...
ObjectivesIschemia-reperfusion injury after lung transplantation is associated with significant morb...
AbstractObjective: Gene transfer to experimental lung grafts has been shown to reduce ischemia-reper...
AbstractObjective: Multiple gene transfer might permit modulation of concurrent biochemical pathways...
OBJECTIVE: Interleukin-1 (IL-1) mediates ischemia-reperfusion injury and graft inflammation after he...
Objective: Interleukin-1 (IL-1) mediates ischemia-reperfusion injury and graft inflammation after he...
AbstractObjective: The objective of this study was to examine the feasibility of human interleukin 1...
AbstractObjective: This study was undertaken to determine whether low-dose endobronchial transfer to...
AbstractObjective: Proximal pulmonary artery segment transfection may provide beneficial downstream ...
AbstractObjective: Nitric oxide regulates vascular tone, inhibits platelet aggregation, and inhibits...
Objective: Electroporation mediated transfer of plasmid DNA into peripheral muscle results in high t...
AbstractBackgroundTumor necrosis factor is an important mediator of lung transplant acute rejection....
AbstractObjectiveTumor necrosis factor is an important mediator of lung transplant ischemia-reperfus...
AbstractBackground: The aim of the current work was to study the feasibility of functional gene tran...
ObjectiveMultiple gene transfer might permit modulation of concurrent biochemical pathways involved ...
none7Objective: Multiple gene transfer might permit modulation of concurrent biochemical pathways in...
ObjectivesIschemia-reperfusion injury after lung transplantation is associated with significant morb...
AbstractObjective: Gene transfer to experimental lung grafts has been shown to reduce ischemia-reper...
AbstractObjective: Multiple gene transfer might permit modulation of concurrent biochemical pathways...
OBJECTIVE: Interleukin-1 (IL-1) mediates ischemia-reperfusion injury and graft inflammation after he...
Objective: Interleukin-1 (IL-1) mediates ischemia-reperfusion injury and graft inflammation after he...
AbstractObjective: The objective of this study was to examine the feasibility of human interleukin 1...
AbstractObjective: This study was undertaken to determine whether low-dose endobronchial transfer to...
AbstractObjective: Proximal pulmonary artery segment transfection may provide beneficial downstream ...
AbstractObjective: Nitric oxide regulates vascular tone, inhibits platelet aggregation, and inhibits...
Objective: Electroporation mediated transfer of plasmid DNA into peripheral muscle results in high t...