AbstractBinding degeneracy (or crossreactivity) constitutes an important attribute of TCR recognition, and crossrecognized ligands consist not only of distinct peptides presented by self-MHC molecules but can also involve MHC molecules belonging to other species. In this issue, Buslepp et al. provide a basis for this trans-species crossreactivity, elucidated by the crystal structure of a complex involving a mouse TCR and a human MHC molecule
The ability of a T cell receptor (TCR) to directly recognize foreign (allogeneic)-major histocompati...
αβ T cell receptors (TCRs) are genetically restricted to corecognize peptide antigens bound to self-...
SummaryT cell-mediated immunity requires T cell receptor (TCR) cross-reactivity, the mechanisms behi...
AbstractBinding degeneracy (or crossreactivity) constitutes an important attribute of TCR recognitio...
SummaryTo test whether highly crossreactive αβ T cell receptors (TCRs) produced during limited negat...
Summaryαβ T cell receptors (TCRs) can crossreact with both self- and foreign- major histocompatibili...
For thymic selection and responses to pathogens, T cells interact through their {alpha}{beta} T cell...
T-cell cross-reactivity is essential for effective immune surveillance, but has also been implicated...
MHC-encoded molecules govern adaptive immune responses by presenting peptides to T cell receptors (T...
T-cell cross-reactivity is essential for effective immune surveillance but has also been implicated ...
SummaryIn order to survey a universe of major histocompatibility complex (MHC)-presented peptide ant...
© 2012 Dr. Sidonia Barbara Guiomar EckleIn the adaptive immune response αβ T cell receptors (TCRs) e...
The T cell receptor (TCR), from a xeno-reactive murine cytotoxic T lymphocyte clone AHIII12.2, recog...
αβ Tcell receptors (TCRs) recognize peptides presented by major histocompatibility complex (MHC) pro...
AbstractT cell receptors (TCR) adopt a similar orientation when binding with major histocompatibilit...
The ability of a T cell receptor (TCR) to directly recognize foreign (allogeneic)-major histocompati...
αβ T cell receptors (TCRs) are genetically restricted to corecognize peptide antigens bound to self-...
SummaryT cell-mediated immunity requires T cell receptor (TCR) cross-reactivity, the mechanisms behi...
AbstractBinding degeneracy (or crossreactivity) constitutes an important attribute of TCR recognitio...
SummaryTo test whether highly crossreactive αβ T cell receptors (TCRs) produced during limited negat...
Summaryαβ T cell receptors (TCRs) can crossreact with both self- and foreign- major histocompatibili...
For thymic selection and responses to pathogens, T cells interact through their {alpha}{beta} T cell...
T-cell cross-reactivity is essential for effective immune surveillance, but has also been implicated...
MHC-encoded molecules govern adaptive immune responses by presenting peptides to T cell receptors (T...
T-cell cross-reactivity is essential for effective immune surveillance but has also been implicated ...
SummaryIn order to survey a universe of major histocompatibility complex (MHC)-presented peptide ant...
© 2012 Dr. Sidonia Barbara Guiomar EckleIn the adaptive immune response αβ T cell receptors (TCRs) e...
The T cell receptor (TCR), from a xeno-reactive murine cytotoxic T lymphocyte clone AHIII12.2, recog...
αβ Tcell receptors (TCRs) recognize peptides presented by major histocompatibility complex (MHC) pro...
AbstractT cell receptors (TCR) adopt a similar orientation when binding with major histocompatibilit...
The ability of a T cell receptor (TCR) to directly recognize foreign (allogeneic)-major histocompati...
αβ T cell receptors (TCRs) are genetically restricted to corecognize peptide antigens bound to self-...
SummaryT cell-mediated immunity requires T cell receptor (TCR) cross-reactivity, the mechanisms behi...
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