The signaling pathway of the cytokine Flt3L in dendritic cells (DCs) is poorly defined. In this issue of Immunity, Sathaliyawala et al. (2010) report that the kinase mTOR functions as a mediator of Flt3L signaling in the development and homeostasis of DCs, particularly of the CD8+ and CD103+ DCs
The ability of Toll-like receptors (TLRs) to activate innate immunity depends on their transport to ...
SummaryThe factors regulating dendritic cell (DC) development and homeostasis are incompletely under...
International audienceT-lymphocyte activation relies on the cognate recognition by the TCR of the MH...
SummaryDendritic cells (DCs) comprise distinct functional subsets including CD8− and CD8+ classical ...
SummaryEffective major histocompatibility complex-II (MHC-II) antigen presentation from phagocytosed...
Both cross-presentation of antigens by dendritic cells, a key pathway triggering T cell immunity and...
SummaryThe transport of Toll-like Receptors (TLRs) to various organelles has emerged as an essential...
We, humans, are exposed daily to millions of potential pathogens, through contact, inhalation, or in...
Mouse dendritic cells (DCs) can rapidly extend their Class II MHC-positive late endosomal compartmen...
SummaryNaive T cells respond to antigens by differentiating into effector and regulatory lineages. W...
NLRP12 is an innate immune receptor whose regulation of NF-κB signaling in myeloid cells is critical...
Movement of immunoreceptor microclusters tunes lymphocyte activation, but the underlying mechanisms ...
CD8+ dendritic cells comprise a distinct cell type whose function is unclear. In this issue of Immun...
Gut lamina propria dendritic cell (DC) subsets have specialized functions. In this issue of Immunity...
SummaryToll-like receptors (TLRs) play prominent roles in initiating immune responses to infection, ...
The ability of Toll-like receptors (TLRs) to activate innate immunity depends on their transport to ...
SummaryThe factors regulating dendritic cell (DC) development and homeostasis are incompletely under...
International audienceT-lymphocyte activation relies on the cognate recognition by the TCR of the MH...
SummaryDendritic cells (DCs) comprise distinct functional subsets including CD8− and CD8+ classical ...
SummaryEffective major histocompatibility complex-II (MHC-II) antigen presentation from phagocytosed...
Both cross-presentation of antigens by dendritic cells, a key pathway triggering T cell immunity and...
SummaryThe transport of Toll-like Receptors (TLRs) to various organelles has emerged as an essential...
We, humans, are exposed daily to millions of potential pathogens, through contact, inhalation, or in...
Mouse dendritic cells (DCs) can rapidly extend their Class II MHC-positive late endosomal compartmen...
SummaryNaive T cells respond to antigens by differentiating into effector and regulatory lineages. W...
NLRP12 is an innate immune receptor whose regulation of NF-κB signaling in myeloid cells is critical...
Movement of immunoreceptor microclusters tunes lymphocyte activation, but the underlying mechanisms ...
CD8+ dendritic cells comprise a distinct cell type whose function is unclear. In this issue of Immun...
Gut lamina propria dendritic cell (DC) subsets have specialized functions. In this issue of Immunity...
SummaryToll-like receptors (TLRs) play prominent roles in initiating immune responses to infection, ...
The ability of Toll-like receptors (TLRs) to activate innate immunity depends on their transport to ...
SummaryThe factors regulating dendritic cell (DC) development and homeostasis are incompletely under...
International audienceT-lymphocyte activation relies on the cognate recognition by the TCR of the MH...
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